AR03
Modify Date: 2024-01-13 19:06:24
AR03 structure
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Common Name | AR03 | ||
|---|---|---|---|---|
| CAS Number | 510721-85-4 | Molecular Weight | 237.30 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H15N3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AR03AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells[1]. |
| Name | 2,4,9-trimethylbenzo[b][1,8]naphthyridin-5-amine |
|---|---|
| Synonym | More Synonyms |
| Description | AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells[1]. |
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| Related Catalog | |
| Target |
IC50: 2.1 µM (Ape1)[1] |
| References |
| Molecular Formula | C15H15N3 |
|---|---|
| Molecular Weight | 237.30 |
| Exact Mass | 237.12700 |
| PSA | 51.80000 |
| LogP | 3.87160 |
| HS Code | 2933990090 |
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| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 2,4,9-Trimethyl-benzo[b][1,8]naphthyridin-5-ylamine |
| HMS2537D20 |