4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one

Modify Date: 2024-01-10 16:49:35

4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one Structure
4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one structure
Common Name 4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one
CAS Number 517-83-9 Molecular Weight 374.43600
Density 1.268g/cm3 Boiling Point 438.6ºC at 760 mmHg
Molecular Formula C22H22N4O2 Melting Point N/A
MSDS N/A Flash Point 166.2ºC

 Names

Name 4-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,5-dimethyl-2-phenylpyrazol-3-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.268g/cm3
Boiling Point 438.6ºC at 760 mmHg
Molecular Formula C22H22N4O2
Molecular Weight 374.43600
Flash Point 166.2ºC
Exact Mass 374.17400
PSA 53.86000
LogP 2.94920
Index of Refraction 1.645

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DW4000000
CHEMICAL NAME :
(4,4'-Bi-3-pyrazoline)-5,5'-dione, 1,1'-diphenyl-2,2',3,3'-tetramethyl-
CAS REGISTRY NUMBER :
517-83-9
BEILSTEIN REFERENCE NO. :
0351034
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H22-N4-O2
MOLECULAR WEIGHT :
374.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
15 gm/kg/22W-I
TOXIC EFFECTS :
Behavioral - ataxia Blood - normocytic anemia Related to Chronic Data - death
REFERENCE :
85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

(4,4'-BI-3-PYRAZOLINE)-5,5'-DIONE,1,1'-DIPHENYL-2,2',3,3'-TETRAMETHYL
2,2',3,3'-Tetramethyl-1,1'-diphenyl(4,4'-bi-3-pyrazoline)-5,5'-dione
Forbisen
S. N. 475
(4,4'-Bi-1H-pyrazole)-3,3'-dione,2,2',3,3'-tetrahydro-1,1',5,5'-tetramethyl-2,2'-diphenyl