CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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WJ5680000
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CHEMICAL NAME :
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4,4'-Stilbenediol, alpha,alpha'-diethyl-, bis(dihydrogen phosphate), (E)-
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CAS REGISTRY NUMBER :
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522-40-7
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LAST UPDATED :
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199504
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DATA ITEMS CITED :
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12
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MOLECULAR FORMULA :
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C18-H22-O8-P2
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MOLECULAR WEIGHT :
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428.34
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WISWESSER LINE NOTATION :
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QPQO&OR DY2&UY2&R DOPQQO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Human - man
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DOSE/DURATION :
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11 mg/kg/3D-I
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TOXIC EFFECTS :
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Vascular - BP lowering not characterized in autonomic section Blood - change in clotting factors Skin and Appendages - sweating
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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3 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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425 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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630 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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400 mg/kg
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SEX/DURATION :
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female 6 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material)
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TYPE OF TEST :
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Cytogenetic analysis
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TYPE OF TEST :
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Sex chromosome loss and nondisjunction
MUTATION DATA
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TYPE OF TEST :
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Mutation test systems - not otherwise specified
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TEST SYSTEM :
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Mammal - species unspecified Lymphocyte
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DOSE/DURATION :
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25 nmol/L
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REFERENCE :
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CYTOAN Cytologia. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1929- Volume(issue)/page/year: 40,817,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3653 No. of Facilities: 86 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 9667 (estimated) No. of Female Employees: 7994 (estimated)
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