7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one

Modify Date: 2024-01-11 16:41:50

7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one structure	Common Name	7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
	CAS Number	52391-89-6	Molecular Weight	318.73000
	Density	1.4g/cm3	Boiling Point	550.3ºC at 760mmHg
	Molecular Formula	C₁₆H₁₂ClFN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	286.6ºC

Name	7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
Synonym	More Synonyms

Density	1.4g/cm3
Boiling Point	550.3ºC at 760mmHg
Molecular Formula	C₁₆H₁₂ClFN₂O₂
Molecular Weight	318.73000
Flash Point	286.6ºC
Exact Mass	318.05700
PSA	52.90000
LogP	2.11190
Index of Refraction	1.641

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DF2370300

CHEMICAL NAME :: 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-m ethyl-

CAS REGISTRY NUMBER :: 52391-89-6

BEILSTEIN REFERENCE NO. :: 0688457

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H12-Cl-F-N2-O2

MOLECULAR WEIGHT :: 318.75

WISWESSER LINE NOTATION :: T67 GNV JN IHJ CG G1 IQ KR BF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHMGBN Pharmacology: International Journal of Experimental and Clinical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1968- Volume(issue)/page/year: 12,74,1974

N/A

CAS#:89722-84-9

7-Chloro-5-(2-f...

CAS#:52391-89-6

Literature: Middleton, W. J.; Bingham, E. M.; Smith, D. H. Journal of Fluorine Chemistry, 1983 , vol. 23, p. 557 - 572

7-chloro-5-(2-f...

CAS#:41300-29-2

7-Chloro-5-(2-f...

CAS#:52391-89-6

Literature: Middleton, W. J.; Bingham, E. M.; Smith, D. H. Journal of Fluorine Chemistry, 1983 , vol. 23, p. 557 - 572

Precursor 1
CAS#:41300-29-2 7-chloro-5-(2-f...
DownStream 0

FLUTEMAZEPAM

Flutemazepam [INN]

Flutemazepamum [Latin]

EINECS 257-892-1

7-Chloro-1,3-dihydro-1-methyl-3-hydroxy-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one

Sas-646

7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one

2H-1,4-Benzodiazepin-2-one,1,3-dihydro-7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl

7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms