N-Hydroxyphthalimide

Modify Date: 2024-01-02 14:32:58

N-Hydroxyphthalimide Structure
N-Hydroxyphthalimide structure
Common Name N-Hydroxyphthalimide
CAS Number 524-38-9 Molecular Weight 163.130
Density 1.6±0.1 g/cm3 Boiling Point 370.3±25.0 °C at 760 mmHg
Molecular Formula C8H5NO3 Melting Point 233 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 177.8±23.2 °C

 Names

Name N-Hydroxyphthalimide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 370.3±25.0 °C at 760 mmHg
Melting Point 233 °C (dec.)(lit.)
Molecular Formula C8H5NO3
Molecular Weight 163.130
Flash Point 177.8±23.2 °C
Exact Mass 163.026947
PSA 57.61000
LogP 0.42
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.718
Storage condition Store at RT.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI5200000
CHEMICAL NAME :
Phthalimide, N-hydroxy-
CAS REGISTRY NUMBER :
524-38-9
BEILSTEIN REFERENCE NO. :
0131208
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H5-N-O3
MOLECULAR WEIGHT :
163.14
WISWESSER LINE NOTATION :
T56 BVNVJ CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
178 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00747

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TI5200000
HS Code 29251995

 Synthetic Route

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles20

More Articles
Bromide-free oxidizing system for carboxylic moiety formation in cellulose chain.

Carbohydr. Polym. 90(4) , 1415-9, (2012)

NHPI (N-hydroxyphthalimide) was used to mediate the oxidation of cellulose fibers in the absence of sodium bromide, as traditionally was used in this kind of transformations, solely using sodium hypoc...

Anthrone-derived NHPI analogues as catalysts in reactions using oxygen as an oxidant.

Org. Biomol. Chem. 6(22) , 4096-8, (2008)

An enantioselective synthesis of anthrone-derived NHPI analogues has been developed. One of these analogues, in combination with Co salts, was employed to catalyse the aerobic oxidation of benzylic co...

Oxidized cellulose--survey of the most recent achievements.

Carbohydr. Polym. 93(1) , 207-15, (2013)

The functionalization and particularly the oxidation of cellulose is an intriguing and challenging topic due to the presence of multiple reactive sites, which can undergo specific reactions. The varie...

 Synonyms

nhpi
N-Hydroxy Phthalimide
2-Hydroxy-1H-isoindole-1,3(2H)-dione
2-hydroxyisoindoline-1,3-dione
N-Hydroxyphthalimide
HOPHT
EINECS 208-358-1
N-hydroxylphthalimide
phthalamohydroxamic acid
PHTHALOXIME
N-hydroxyphtalimide
n-hydroxy-phthalimid
MFCD00005891
hydroxyphthalimide
NHPI NOP
1H-Isoindole-1,3(2H)-dione, 2-hydroxy-
N-hydroxy-phthalimide
2-hydroxy-1,3-isoindolinedione
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