2,7-Diaminofluorene

Modify Date: 2024-01-07 12:51:31

2,7-Diaminofluorene Structure
2,7-Diaminofluorene structure
Common Name 2,7-Diaminofluorene
CAS Number 525-64-4 Molecular Weight 196.248
Density 1.3±0.1 g/cm3 Boiling Point 467.0±38.0 °C at 760 mmHg
Molecular Formula C13H12N2 Melting Point 160-162 °C(lit.)
MSDS Chinese USA Flash Point 283.6±26.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2,7-Diaminofluorene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 467.0±38.0 °C at 760 mmHg
Melting Point 160-162 °C(lit.)
Molecular Formula C13H12N2
Molecular Weight 196.248
Flash Point 283.6±26.3 °C
Exact Mass 196.100052
PSA 52.04000
LogP 1.60
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.750

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LL6980000
CHEMICAL NAME :
Fluorene-2,7-diamine
CAS REGISTRY NUMBER :
525-64-4
LAST UPDATED :
199709
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C13-H12-N2
MOLECULAR WEIGHT :
196.27
WISWESSER LINE NOTATION :
L B656 HHJ EZ KZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1000 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3600 mg/kg/27D-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
DNA repair
TYPE OF TEST :
Mutation test systems - not otherwise specified
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
80 ug/L
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5160 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 16 (estimated) No. of Female Employees: 16 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LL6980000
HS Code 2921590090

 Synthetic Route

 Customs

HS Code 2921590090
Summary 2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles12

More Articles
Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test.

Mutat. Res. 290(2) , 175-82, (1993)

Drosophila melanogaster stock consisting of meiotic recombination deficient (Rec-) double mutant mei-9a mei-41D5 males and Rec+ females was exposed at the larval stage to an aromatic amine or a polycy...

[An interesting peroxidase staining.--utilization of blended substrate of mixed 2, 7-FDA and Laurent's acid-- (author's transl)].

Rinsho Byori. 29(6) , 613-6, (1981)

Sensitive assay systems for detection of hemoglobin with 2,7-diaminofluorene: histochemistry and colorimetry for erythrodifferentiation.

Anal. Biochem. 149 , 117, (1985)

Sensitive and rapid assays, colorimetry and histochemistry, for hemoglobin in erythroid cells are established. The assays are based on pseudoperoxidase activity of hemoglobin using 2,7-diaminofluorene...

 Synonyms

2,7-diamine-9H-fluorene
Diaminofluorene
2,7-FLUORENEDIAMINE
7-amino-9H-fluoren-2-ylamine
MFCD00001128
DAF
2,5-DIMETHYL-4-METHOXYBENZENEBORONIC ACID
2,7-Diaminofluorene
9H-Fluorene-2,7-diamine
EINECS 208-377-5
fluorene-2,7-diyldiamine
2,7-DiaMinoflyorene
fluorene-2,7-diamine
9H-Fluorene-2,7-diamine (9CI)
2,7-diamino-9H-fluorene
2,7-DIAMINO-FLUOROENE
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