Nicotinamide adenine dinucleotide phosphate

Modify Date: 2024-01-03 09:26:03

Nicotinamide adenine dinucleotide phosphate Structure
Nicotinamide adenine dinucleotide phosphate structure
Common Name Nicotinamide adenine dinucleotide phosphate
CAS Number 53-59-8 Molecular Weight 744.41
Density N/A Boiling Point N/A
Molecular Formula C21H29N7O17P3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nicotinamide adenine dinucleotide phosphate


NADP is nicotinamide adenine dinucleotide phosphate, acting as a key cofactor for electron transfer in the metabolism of all organisms, being alternately oxidized (NADP+) and reduced (NADPH).

 Names

Name NADP zwitterion
Synonym More Synonyms

  Biological Activity

Description NADP is nicotinamide adenine dinucleotide phosphate, acting as a key cofactor for electron transfer in the metabolism of all organisms, being alternately oxidized (NADP+) and reduced (NADPH).
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Zhao FL, et al. A genetically encoded biosensor for in vitro and in vivo detection of NADP+. Biosens Bioelectron. 2016 Mar 15;77:901-6.

 Chemical & Physical Properties

Molecular Formula C21H29N7O17P3
Molecular Weight 744.41
PSA 397.05000
LogP -7.30
Storage condition −20°C
Water Solubility H2O: 50 mg/mL, clear, slightly yellow

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU3440000
CHEMICAL NAME :
Pyridinium, 3-carbamoyl-1-beta-D-ribofuranosyl-, hydroxide, 5',5'-ester with adenosine 2'- (dihydrogen phosphate) 5'-(trihydrogen pyrophosphate), inner salt
CAS REGISTRY NUMBER :
53-59-8
BEILSTEIN REFERENCE NO. :
3885115
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C21-H28-N7-O17-P3
MOLECULAR WEIGHT :
743.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3166 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 20,160,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1187 No. of Facilities: 58 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 332 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1187 No. of Facilities: 327 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 4926 (estimated) No. of Female Employees: 3928 (estimated)

 Safety Information

Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
WGK Germany 3
RTECS UU3440000
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

NADPH
NADP-ox
NADP+
COENZYME II
b-Nicotinamide Adenine Dinucleotide Phosphate
cozymaseii
β-Nicotinamide Adenine Dinucleotide Phosphate
TPNH
b-NADP
β-Triphosphopyridine Nucleotide
TPN
Triphosphopyridinnucleotid
3-Carbamoyl-1-b-D-ribofuranosylpyridinium Hydroxide 5'®5'-Ester with Adenosine 2'-(Dihydrogen Phosphate) 5'-(Trihydrogen Pyrophosphate) Inner Salt
Co II
Adenosine 5'-(Trihydrogen Diphosphate) 2'-(Dihydrogen Phosphate) P'®5'-Ester with 3-(Aminocarbonyl)-1-b-D-ribofuranosylpyridinium Hydroxide Inner Salt
Beta-NADP,Monopotassium Salt
MFCD10567218
NADP
b-TPN
β-Nicotinamide adenine dinucleotide phosphate (NADP)
Triphosphopyridine Nucleotid
Triphosphopyridine nucleotide
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