(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester

Modify Date: 2024-01-08 11:55:05

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure
(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester structure
Common Name (5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester
CAS Number 535170-18-4 Molecular Weight 226.24700
Density 1.223g/cm3 Boiling Point 291.79°C at 760 mmHg
Molecular Formula C11H15FN2O2 Melting Point N/A
MSDS N/A Flash Point 130.27°C

 Names

Name tert-butyl N-(5-amino-2-fluorophenyl)carbamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.223g/cm3
Boiling Point 291.79°C at 760 mmHg
Molecular Formula C11H15FN2O2
Molecular Weight 226.24700
Flash Point 130.27°C
Exact Mass 226.11200
PSA 64.35000
LogP 3.40910
Index of Refraction 1.566

 Safety Information

Hazard Codes Xn
Risk Phrases 22
HS Code 2924299090

 Synthetic Route

~87%

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917

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(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: Hirose, Masaaki; Okaniwa, Masanori; Miyazaki, Tohru; Imada, Takashi; Ohashi, Tomohiro; Tanaka, Yuta; Arita, Takeo; Yabuki, Masato; Kawamoto, Tomohiro; Tsutsumi, Shunichirou; Sumita, Akihiko; Takagi, Terufumi; Sang, Bi-Ching; Yano, Jason; Aertgeerts, Kathleen; Yoshida, Sei; Ishikawa, Tomoyasu Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 18 p. 5600 - 5615

~%

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: Hirose, Masaaki; Okaniwa, Masanori; Miyazaki, Tohru; Imada, Takashi; Ohashi, Tomohiro; Tanaka, Yuta; Arita, Takeo; Yabuki, Masato; Kawamoto, Tomohiro; Tsutsumi, Shunichirou; Sumita, Akihiko; Takagi, Terufumi; Sang, Bi-Ching; Yano, Jason; Aertgeerts, Kathleen; Yoshida, Sei; Ishikawa, Tomoyasu Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 18 p. 5600 - 5615

~%

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917

~%

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917

~%

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: Kuramoto, Yasuhiro; Ohshita, Yoshihiro; Yoshida, Jiro; Yazaki, Akira; Shiro, Motoo; Koike, Tohru Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1905 - 1917

~%

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Yingjun; ZHANG, Jiancun; WANG, Xiaojun; LIN, Runfeng; CAO, Shengtian; WANG, Zhaohe; LI, Jing Patent: WO2014/12360 A1, 2014 ;

~%

(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester Structure

(5-Amino-2-fluo...

CAS#:535170-18-4

Literature: SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Yingjun; ZHANG, Jiancun; WANG, Xiaojun; LIN, Runfeng; CAO, Shengtian; WANG, Zhaohe; LI, Jing Patent: WO2014/12360 A1, 2014 ;

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2-Methyl-2-Propanyl (5-Amino-2-Fluorophenyl)Carbamate
(5-Amino-2-fluorophenyl)-carbamic acid tert-butyl ester