Vinformide

Modify Date: 2024-01-08 16:27:58

Vinformide Structure
Vinformide structure
Common Name Vinformide
CAS Number 54022-49-0 Molecular Weight 822.94200
Density 1.42g/cm3 Boiling Point N/A
Molecular Formula C46H54N4O10 Melting Point 200-210ºC
MSDS N/A Flash Point N/A

 Use of Vinformide


Vinformide is a potent cytostatic agent.

 Names

Name N-Formyl Leurosine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.42g/cm3
Melting Point 200-210ºC
Molecular Formula C46H54N4O10
Molecular Weight 822.94200
Exact Mass 822.38400
PSA 163.47000
LogP 4.11060
Index of Refraction 1.684

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LR2962000
CHEMICAL NAME :
Formyl-leurosine
CAS REGISTRY NUMBER :
54022-49-0
LAST UPDATED :
198910
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C46-H54-N4-O10
MOLECULAR WEIGHT :
823.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
500 ug/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Rodent - mouse Ascites tumor
DOSE/DURATION :
10 mg/kg
REFERENCE :
EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 19,1113,1983

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

Formyl-leurosine