Palmitoylethanolamide

Modify Date: 2024-01-02 17:53:08

Palmitoylethanolamide Structure
Palmitoylethanolamide structure
Common Name Palmitoylethanolamide
CAS Number 544-31-0 Molecular Weight 299.492
Density 0.9±0.1 g/cm3 Boiling Point 461.5±28.0 °C at 760 mmHg
Molecular Formula C18H37NO2 Melting Point 99 °C
MSDS Chinese USA Flash Point 232.9±24.0 °C

 Use of Palmitoylethanolamide


AM 3112 is an active endogenous compound which can used for preventing virus infection of the respiratory tract.

 Names

Name palmitoyl ethanolamide
Synonym More Synonyms

 Palmitoylethanolamide Biological Activity

Description AM 3112 is an active endogenous compound which can used for preventing virus infection of the respiratory tract.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro AM 3112 (Impulsin) itself does not stimulate interferon production in mice treated per os or intravenously. But repeated application of this drug per os induces a macrophage activation, reflected by enhanced interferon production in vitro. When the interferon stimulation is delayed until 4 to 10 days after the first dose of AM 3112, interferon response to ds-RNA is slightly increased. After this phase of enhanced activity a decreased production of interferon is observed. AM 3112 is not significantly effective in protecting mice from lethal dose of EMC virus. Application of this drug has an inhibitory effect on the toxicity of ds-RNA. A possible explanation of the mechanism by which AM 3112 decreased the toxicity of virus in the organism is discussed[1].
References

[1]. Lackovic V, et al. Effect of impulsin treatment of interferon production and antiviral resistance of mice. Arch Immunol Ther Exp (Warsz). 1977;25(5):655-61.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 461.5±28.0 °C at 760 mmHg
Melting Point 99 °C
Molecular Formula C18H37NO2
Molecular Weight 299.492
Flash Point 232.9±24.0 °C
Exact Mass 299.282440
PSA 49.33000
LogP 5.82
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.463

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 2
HS Code 2924199090

 Synthetic Route

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles96

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The aim of this study is to investigate in vitro interactions between hydrophobic acrylate intraocular lenses (IOLs) and their biological environment. The influence of lens chemical composition and ag...

Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways.

Thromb. Haemost. 113(4) , 838-50, (2015)

Paradoxically, morbid obesity was suggested to protect from cardiovascular co-morbidities as compared to overweight/obese patients. We hypothesise that this paradox could be inferred to modulation of ...

Superparamagnetic core-shells anchored onto graphene oxide grafted with phenylethyl amine as a nano-adsorbent for extraction and enrichment of organophosphorus pesticides from fruit, vegetable and water samples.

J. Chromatogr. A. 1406 , 48-58, (2015)

A novel adsorbent composed of silica coated magnetic microparticles (Fe3O4@SiO2) and graphene oxide (GO) functionalized with phenylethyl amine (PEA) was synthesized and characterized using Fourier tra...

 Synonyms

Palmitoyl Ethanolamide
Palmitoylethanolamide
palmidrol
EINECS 208-867-9
N-(2-Hydroxyethyl)hexadecanamide
MFCD00020562
Hexadecanamide, N-(2-hydroxyethyl)-
AM 3112
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Price: ¥550/10 mM * 1 mL in DMSO

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