Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-

Modify Date: 2022-04-08 09:51:08

Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)- Structure
Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)- structure
Common Name Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-
CAS Number 545-84-6 Molecular Weight 384.46900
Density 1.32g/cm3 Boiling Point 542.9ºC at 760 mmHg
Molecular Formula C22H28N2O4 Melting Point N/A
MSDS N/A Flash Point 282.1ºC

 Use of Ibogamine-18-carboxylicacid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-


(–)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 g/ml).

 Names

Name voacangarine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.32g/cm3
Boiling Point 542.9ºC at 760 mmHg
Molecular Formula C22H28N2O4
Molecular Weight 384.46900
Flash Point 282.1ºC
Exact Mass 384.20500
PSA 74.79000
LogP 2.17250
Index of Refraction 1.648

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NH6737100
CHEMICAL NAME :
Ibogamine-18-carboxylic acid, 20-hydroxy-12-methoxy-, methyl ester, (20S)-
CAS REGISTRY NUMBER :
545-84-6
LAST UPDATED :
199410
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H28-N2-O4
MOLECULAR WEIGHT :
384.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
100 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 171,17,1986

 Synonyms

COACRISTINE
voacristine
Voacangarin
20-hydroxy-12-methoxy-ibogamine-18-carboxylic acid methyl ester
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