1H-Benz[de]isoquinoline-1,3(2H)-dione,5-nitro-2-[2-(1-pyrrolidinyl)ethyl]-

MOLECULAR FORMULA :

C18-H17-N3-O4

MOLECULAR WEIGHT :

339.38

WISWESSER LINE NOTATION :

T666 1A M CVNVJ D2- AT5NTJ& HNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4500 ug/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

12600 ug/kg

TOXIC EFFECTS :

Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :

Mutation test systems - not otherwise specified

TEST SYSTEM :

Rodent - mouse Ascites tumor

DOSE/DURATION :

3 mg/L

REFERENCE :

CCPHDZ Cancer Chemotherapy and Pharmacology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1978- Volume(issue)/page/year: 4,61,1980