Nε,Nε,Nε-Trimethyllysine chloride

Modify Date: 2024-01-14 11:39:55

Nε,Nε,Nε-Trimethyllysine chloride Structure
Nε,Nε,Nε-Trimethyllysine chloride structure
Common Name Nε,Nε,Nε-Trimethyllysine chloride
CAS Number 55528-53-5 Molecular Weight 224.72800
Density N/A Boiling Point N/A
Molecular Formula C9H21ClN2O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Nε,Nε,Nε-Trimethyllysine chloride


Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[1].

 Names

Name Nε,Nε,Nε-Trimethyllysine hydrochloride
Synonym More Synonyms

 Nε,Nε,Nε-Trimethyllysine chloride Biological Activity

Description Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[1].
Related Catalog
In Vitro TMAVA as a novel gut flora metabolite generated from Nε,Nε,Nε-Trimethyllysine chloride[1].
References

[1]. Zhao M, et al. TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice. Gastroenterology. 2020;158(8):2266-2281.e27.

 Chemical & Physical Properties

Molecular Formula C9H21ClN2O2
Molecular Weight 224.72800
Exact Mass 224.12900
PSA 66.15000
LogP 0.44240
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles32

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Inhibition of histone binding by supramolecular hosts.

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The tandem PHD (plant homeodomain) fingers of the CHD4 (chromodomain helicase DNA-binding protein 4) ATPase are epigenetic readers that bind either unmodified histone H3 tails or H3K9me3 (histone H3 t...

A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A.

Biochem. Biophys. Res. Commun. 455(3-4) , 382-9, (2014)

The elongation factors of Saccharomyces cerevisiae are extensively methylated, containing a total of ten methyllysine residues. Elongation factor methyltransferases (Efm1, Efm2, Efm3, and Efm4) cataly...

Tuning HP1α chromodomain selectivity for di- and trimethyllysine.

ChemBioChem. 12(18) , 2786-90, (2011)

Histone lysine methylation is a critical marker for controlling gene expression. The position and extent of methylation (mono-, di-, or tri-) controls the binding of effector proteins that determine w...

 Synonyms

[(5S)-5-amino-5-carboxypentyl]-trimethylazanium,chloride
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