Exaprolol

Modify Date: 2024-01-04 16:42:21

Exaprolol Structure
Exaprolol structure
Common Name Exaprolol
CAS Number 55837-19-9 Molecular Weight 291.42800
Density 1.025g/cm3 Boiling Point 445.2ºC at 760 mmHg
Molecular Formula C18H29NO2 Melting Point N/A
MSDS N/A Flash Point 223.1ºC

 Names

Name 1-(2-cyclohexylphenoxy)-3-(propan-2-ylamino)propan-2-ol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.025g/cm3
Boiling Point 445.2ºC at 760 mmHg
Molecular Formula C18H29NO2
Molecular Weight 291.42800
Flash Point 223.1ºC
Exact Mass 291.22000
PSA 41.49000
LogP 3.86290
Index of Refraction 1.524

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UA9812800
CHEMICAL NAME :
2-Propanol, 1-(2-cyclohexylphenoxy)-3-((1-methylethyl)amino)-
CAS REGISTRY NUMBER :
55837-19-9
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H29-N-O2
MOLECULAR WEIGHT :
291.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
65 mg/kg
SEX/DURATION :
female 4-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
BLLIAX Bratislavske Lekarske Listy. (PNS-Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.1- 1921- Volume(issue)/page/year: 76,664,1981
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
130 mg/kg
SEX/DURATION :
female 4-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
BLLIAX Bratislavske Lekarske Listy. (PNS-Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.1- 1921- Volume(issue)/page/year: 76,664,1981

 Synthetic Route

~%

Exaprolol Structure

Exaprolol

CAS#:55837-19-9

Literature: Jendrichovsky; Rybar; Stibranyi; et al. Collection of Czechoslovak Chemical Communications, 1978 , vol. 43, # 4 p. 1100 - 1107

~%

Exaprolol Structure

Exaprolol

CAS#:55837-19-9

Literature: Carissimi; Gentili; Grumelli; Milla; Picciola; Ravenna Arzneimittel-Forschung/Drug Research, 1976 , vol. 26, # 4 p. 506 - 516

 Synonyms

exaprolol
Exaprolol [INN]
Exaprololum [INN-Latin]
2-Propanol,1-(2-cyclohexylphenoxy)-3-((1-methylethyl)amino)
1-(2-Cyclohexylphenoxy)-3-((1-methylethyl)amino)-2-propanol
1-Isopropylamino-3-(2-cyclohexylphenoxy)-2-propanol
1-(O-Cyklohexyl)fenoxy-3-izopropyl(aminopropan-1-ol) [Czech]
Esaprololo [DCIT]
Vulm 111