2-(Fluoroacetyl)-3-(2-methylphenyl)-6-nitroquinazolin-4(3H)-one

Modify Date: 2024-01-11 17:48:59

2-(Fluoroacetyl)-3-(2-methylphenyl)-6-nitroquinazolin-4(3H)-one Structure
2-(Fluoroacetyl)-3-(2-methylphenyl)-6-nitroquinazolin-4(3H)-one structure
Common Name 2-(Fluoroacetyl)-3-(2-methylphenyl)-6-nitroquinazolin-4(3H)-one
CAS Number 56287-73-1 Molecular Weight 313.28300
Density 1.39g/cm3 Boiling Point 488.8ºC at 760mmHg
Molecular Formula C16H12FN3O3 Melting Point 156-158 °C
MSDS N/A Flash Point 249.4ºC

 Names

Name 2-(fluoromethyl)-3-(2-methylphenyl)-6-nitroquinazolin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.39g/cm3
Boiling Point 488.8ºC at 760mmHg
Melting Point 156-158 °C
Molecular Formula C16H12FN3O3
Molecular Weight 313.28300
Flash Point 249.4ºC
Exact Mass 313.08600
PSA 80.71000
LogP 3.59500
Index of Refraction 1.648

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA3388850
CHEMICAL NAME :
4(3H)-Quinazolinone, 2-(fluoromethyl)-3-(2-methylphenyl)-6-nitro-
CAS REGISTRY NUMBER :
56287-73-1
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H12-F-N3-O3
MOLECULAR WEIGHT :
313.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,95,1979

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

~99%

2-(Fluoroacetyl)-3-(2-methylphenyl)-6-nitroquinazolin-4(3H)-one Structure

2-(Fluoroacetyl...

CAS#:56287-73-1

Literature: Tanabe Seiyaku Co., Ltd. Patent: US3966731 A1, 1976 ;

 Precursor & DownStream

Precursor  1

DownStream  1

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-(FLUOROMETHYL)-3-(2-METHYLPHENYL)-6-NITRO-3H-QUINAZOLIN-4-ONE
2-(Fluoromethyl)-3-(2-methylphenyl)-6-nitro-4(3H)-quinazolinone
2-fluoromethyl-6-nitro-3-o-tolyl-3H-quinazolin-4-one
2-fluoromethyl-3-(o-tolyl)-6-nitro-4(3H)-quinazolinone
2-fluoromethyl-3-(o-hydroxymethylphenyl)-6-nitro-4(3H)-quinazolinone
4(3H)-Quinazolinone,2-(fluoromethyl)-3-(2-methylphenyl)-6-nitro