Tert-buthyl Pitavastatin

Modify Date: 2024-01-08 17:19:58

Tert-buthyl Pitavastatin Structure
Tert-buthyl Pitavastatin structure
 Common Name Tert-buthyl Pitavastatin
CAS Number 586966-54-3 Molecular Weight 477.567
Density 1.2±0.1 g/cm3 Boiling Point 674.5±55.0 °C at 760 mmHg
Molecular Formula C29H32FNO4 Melting Point N/A
MSDS N/A Flash Point 361.7±31.5 °C

 Use of Tert-buthyl Pitavastatin


tert-Buthyl Pitavastatin is the  metabolite of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor[1].

 Names

Name Tert-buthyl Pitavastatin
Synonym More Synonyms

 Tert-buthyl Pitavastatin Biological Activity

Description tert-Buthyl Pitavastatin is the  metabolite of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor[1].
Related Catalog
References

[1]. Morikawa S, et al. Relative induction of mRNA for HMG CoA reductase and LDL receptor by five different HMG-CoA reductase inhibitors in cultured human cells. J Atheroscler Thromb. 2000;7(3):138-44.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 674.5±55.0 °C at 760 mmHg
Molecular Formula C29H32FNO4
Molecular Weight 477.567
Flash Point 361.7±31.5 °C
Exact Mass 477.231537
PSA 79.65000
LogP 5.26
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.624

 Synonyms

(3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-6(E)-heptanoic acid tert-butyl ester
tert-butyl (3R,5S,E)-7-(2-chloropropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
Tert-butyl Pitavastatin
6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-
pitavastatin tert butyl ester
2-Methyl-2-propanyl (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate
(3R,5S,6E)7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydrosy-6-heptaneacid,ethylester
(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid tert-butyl ester
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