A2315A

Modify Date: 2024-01-09 17:19:30

A2315A Structure
A2315A structure
Common Name A2315A
CAS Number 58717-24-1 Molecular Weight 503.58800
Density N/A Boiling Point N/A
Molecular Formula C26H37N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A2315A


A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation[1].

 Names

Name (3R,5S,6E,8E,13E,15R,16R,19R)-3,5-dihydroxy-7,15,19-trimethyl-16-propan-2-yl-17,24-dioxa-11,20,25-triazabicyclo[20.2.1]pentacosa-1(25),6,8,13,22-pentaene-12,18,21-trione
Synonym More Synonyms

 A2315A Biological Activity

Description A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation[1].
Related Catalog
References

[1]. Osterman IA, et, al. Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res. 2017 Jul 7;45(12):7507-7514.  

 Chemical & Physical Properties

Molecular Formula C26H37N3O7
Molecular Weight 503.58800
Exact Mass 503.26300
PSA 157.97000
LogP 2.12600

 Synonyms

Antibiotic A 2315A
Madumycin II
A2315A
A-2315
Antibiotic A 2315
Madumicin II