Analgin

Modify Date: 2024-01-06 14:58:55

Analgin Structure
Analgin structure
Common Name Analgin
CAS Number 5907-38-0 Molecular Weight 351.35
Density N/A Boiling Point N/A
Molecular Formula C13H18N3NaO5S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Warning

 Use of Analgin


Metamizole (Dipyrone) sodium hydrate is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).Target: COXDipyrone is a potent analgesic and antipyretic drug that has been used clinically for more than 80 years.

 Names

Name Dipyron hydrate
Synonym More Synonyms

 Analgin Biological Activity

Description Metamizole (Dipyrone) sodium hydrate is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).Target: COXDipyrone is a potent analgesic and antipyretic drug that has been used clinically for more than 80 years.
Related Catalog
References

[1]. Pierre SC, et al. Inhibition of cyclooxygenases by dipyrone. Br J Pharmacol. 2007 Jun;151(4):494-503.

 Chemical & Physical Properties

Molecular Formula C13H18N3NaO5S
Molecular Weight 351.35
PSA 95.75000
LogP 1.50410
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PB1320000
CHEMICAL NAME :
Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt, monohydrate
CAS REGISTRY NUMBER :
5907-38-0
LAST UPDATED :
199507
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H17-N3-O4-S.H2-O.Na
MOLECULAR WEIGHT :
352.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
70 gm/kg/25W (Continuous)
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 12,1221,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5829 No. of Facilities: 422 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 4405 (estimated) No. of Female Employees: 2165 (estimated)

 Safety Information

Symbol GHS08
GHS08
Signal Word Warning
Hazard Statements H361
Precautionary Statements P280
Personal Protective Equipment Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xn: Harmful;
Risk Phrases R63
Safety Phrases S36/37
RIDADR NONH for all modes of transport
RTECS PB1320000
HS Code 2933192000

 Synthetic Route

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Analgin Structure

Analgin

CAS#:5907-38-0

Literature: DE476663 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2449

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Analgin Structure

Analgin

CAS#:5907-38-0

Literature: DE476663 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2449

 Customs

HS Code 2933192000

 Articles4

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 Synonyms

Dipyrone monohydrate
Analgin
Metamizol monohydrate
1-Phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate Sodium Monohydrate
Noraminopyrine Methanesulfonate Sodium Monohydrate
Sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)
MFCD00150293
EINECS 200-694-7
(Antipyrinylmethylamino)methanesulfonic acid sodium salt monohydrate
Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt, hydrate (1:1:1)
Sodium Methylaminoantipyrine Methanesulfonate Monohydrate
Metamizole (sodium hydrate)
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