NEK6 inibitor 8
Modify Date: 2024-01-15 00:25:54
NEK6 inibitor 8 structure
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Common Name | NEK6 inibitor 8 | ||
|---|---|---|---|---|
| CAS Number | 591239-68-8 | Molecular Weight | 304.299 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 504.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C18H12N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 259.2±30.1 °C | |
Use of NEK6 inibitor 8NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9; dispalys antiproliferative activity against a panel of human cancer cell lines (IC50 <100 uM). |
| Name | (5Z)-2-Hydroxy-4-methyl-6-oxo-5-[(5-phenyl-2-furyl)methylene]-5,6-dihydropyridine-3-carbonitrile |
|---|---|
| Synonym | More Synonyms |
| Description | NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-related kinase NEK6 with IC50 of 3.4 uM, compound 8 is very selective against NEK1 and NEK6, while no signifcant activity was observed against NEK2, NEK7, and NEK9; dispalys antiproliferative activity against a panel of human cancer cell lines (IC50 <100 uM). |
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| References | References 1. De Donato M, et al. Sci Rep. 2018 Oct 30;8(1):16047. View Related Products by Target Other Targets |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 504.9±50.0 °C at 760 mmHg |
| Molecular Formula | C18H12N2O3 |
| Molecular Weight | 304.299 |
| Flash Point | 259.2±30.1 °C |
| Exact Mass | 304.084778 |
| LogP | 3.44 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.646 |
| (5Z)-2-Hydroxy-4-methyl-6-oxo-5-[(5-phenyl-2-furyl)methylene]-5,6-dihydropyridine-3-carbonitrile |
| 3-Pyridinecarbonitrile, 1,2,5,6-tetrahydro-4-methyl-2,6-dioxo-5-[(5-phenyl-2-furanyl)methylene]-, (5Z)- |
| 3-pyridinecarbonitrile, 5,6-dihydro-2-hydroxy-4-methyl-6-oxo-5-[(5-phenyl-2-furanyl)methylene]-, (5Z)- |
| (5Z)-4-Methyl-2,6-dioxo-5-[(5-phenyl-2-furyl)methylene]-1,2,5,6-tetrahydro-3-pyridinecarbonitrile |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: NEK6 inhibitor 8
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: NEK6 inhibitor 8
- Price: $400.0/10mg $700.0/25mg $950.0/50mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: NEK6 inhibitor 8
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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