N-Butylurea

Modify Date: 2024-01-02 18:30:36

N-Butylurea Structure
N-Butylurea structure
Common Name N-Butylurea
CAS Number 592-31-4 Molecular Weight 116.16200
Density 0.962 g/cm3 Boiling Point 179.4ºC at 760 mmHg
Molecular Formula C5H12N2O Melting Point 95-98 °C(lit.)
MSDS Chinese USA Flash Point 62.3ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name butylurea
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.962 g/cm3
Boiling Point 179.4ºC at 760 mmHg
Melting Point 95-98 °C(lit.)
Molecular Formula C5H12N2O
Molecular Weight 116.16200
Flash Point 62.3ºC
Exact Mass 116.09500
PSA 55.12000
LogP 1.54600
Index of Refraction 1.449
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS3675000
CHEMICAL NAME :
Urea, butyl-
CAS REGISTRY NUMBER :
592-31-4
BEILSTEIN REFERENCE NO. :
1744775
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C5-H12-N2-O
MOLECULAR WEIGHT :
116.19
WISWESSER LINE NOTATION :
ZVM4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1255 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
382 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1285 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1627 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Fibroblast
DOSE/DURATION :
4 gm/L/48H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 48,337,1977

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22;R37;R68
Safety Phrases S45-S36/37
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YS3675000
HS Code 2924199090

 Synthetic Route

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles11

More Articles
A quadruply hydrogen bonded heterocomplex displaying high-fidelity recognition.

J. Am. Chem. Soc. 127(51) , 18133-42, (2005)

An exceptionally strong quadruply hydrogen-bonded complex is formed between 2,7-diamido-1,8-naphthyridine 3 (DAN) and the butylurea of guanosine 6 (UG) in chloroform. The UG unit can be prepared in fo...

Comparative evaluation of fifteen anti-sickling agents.

Blood 61(4) , 693-704, (1983)

Fifteen compounds reported to be inhibitors of gelation or sickling were studied by standard methods. These tests included (1) the determination of the solubility of deoxyhemoglobin S or Csat, (2) eva...

Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease.

Bioorg. Med. Chem. 11(22) , 4769-77, (2003)

The human immunodeficiency virus (HIV) has been shown to be the causative agent for AIDS. The HIV virus encodes for a unique aspartyl protease that is essential for the production of enzymes and prote...

 Synonyms

EINECS 209-748-4
Urea,butyl
1-Butylurea
MFCD00007956
Urea,N-butyl
butylamine amide
1-n-butylurea
N-BUTYLUREA
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