6-FLUOROBENZO(a)PYRENE

Modify Date: 2024-01-09 18:44:50

6-FLUOROBENZO(a)PYRENE Structure
6-FLUOROBENZO(a)PYRENE structure
Common Name 6-FLUOROBENZO(a)PYRENE
CAS Number 59417-86-6 Molecular Weight 270.30000
Density 1.349g/cm3 Boiling Point 470.4ºC at 760 mmHg
Molecular Formula C20H11F Melting Point N/A
MSDS N/A Flash Point 203.5ºC

 Names

Name 6-fluorobenzo[a]pyrene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.349g/cm3
Boiling Point 470.4ºC at 760 mmHg
Molecular Formula C20H11F
Molecular Weight 270.30000
Flash Point 203.5ºC
Exact Mass 270.08400
LogP 5.87630
Index of Refraction 1.86

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ6380270
CHEMICAL NAME :
Benzo(a)pyrene, 6-fluoro-
CAS REGISTRY NUMBER :
59417-86-6
LAST UPDATED :
199706
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H11-F
MOLECULAR WEIGHT :
270.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
35 mg/kg/1W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
49 mg/kg/60W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
16 mg/kg/60W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983

 Synthetic Route

~21%

6-FLUOROBENZO(a)PYRENE Structure

6-FLUOROBENZO(a...

CAS#:59417-86-6

Literature: Laali, Kenneth K.; Tanaka, Mutsuo; Forohar, Farhad; Cheng, Michael; Fetzer, John C. Journal of Fluorine Chemistry, 1998 , vol. 91, # 2 p. 185 - 190

~%

6-FLUOROBENZO(a)PYRENE Structure

6-FLUOROBENZO(a...

CAS#:59417-86-6

Literature: Cremonesi, Paolo; Cavalieri, Ercole L.; Rogan, Eleanor G. Journal of Organic Chemistry, 1989 , vol. 54, # 15 p. 3561 - 3570

 Synonyms

6-Fluorobenzo(a)pyrene
Benzo(a)pyrene,6-fluoro