1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one

Modify Date: 2024-01-08 18:07:35

1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one Structure
1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one structure
Common Name 1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one
CAS Number 59892-37-4 Molecular Weight 584.53
Density N/A Boiling Point N/A
Molecular Formula C31H24N2O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one


5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-5-nitropyridin-2-one
Synonym More Synonyms

  Biological Activity

Description 5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C31H24N2O10
Molecular Weight 584.53
Exact Mass 584.14300
PSA 155.95000
LogP 4.48530

 Synonyms

1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
5-nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2-pyridone