1,1'-Pentamethylenebis[3-(2-chloroethyl)-3-nitrosourea]

Modify Date: 2024-04-02 13:36:54

1,1'-Pentamethylenebis[3-(2-chloroethyl)-3-nitrosourea] Structure
1,1'-Pentamethylenebis[3-(2-chloroethyl)-3-nitrosourea] structure
Common Name 1,1'-Pentamethylenebis[3-(2-chloroethyl)-3-nitrosourea]
CAS Number 60784-44-3 Molecular Weight 371.22000
Density 1.43g/cm3 Boiling Point N/A
Molecular Formula C11H20Cl2N6O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 1-(2-chloroethyl)-3-[5-[[2-chloroethyl(nitroso)carbamoyl]amino]pentyl]-1-nitrosourea

 Chemical & Physical Properties

Density 1.43g/cm3
Molecular Formula C11H20Cl2N6O4
Molecular Weight 371.22000
Exact Mass 370.09200
PSA 130.52000
LogP 2.42910
Index of Refraction 1.581

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YT9955000
CHEMICAL NAME :
Urea, 1,1'-pentamethylenebis(3-(2-chloroethyl)-3-nitroso-
CAS REGISTRY NUMBER :
60784-44-3
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C11-H20-Cl2-N6-O4
MOLECULAR WEIGHT :
371.27
WISWESSER LINE NOTATION :
ONN2GVM5MVNNO&2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
45 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - hepatitis (hepatocellular necrosis), diffuse Blood - changes in bone marrow (not otherwise specified)
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
Gene conversion and mitotic recombination
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
500 umol/L/16H
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,45,1977
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