5-Methylindoline-2,3-dione

Modify Date: 2024-01-02 18:56:14

5-Methylindoline-2,3-dione structure	Common Name	5-Methylindoline-2,3-dione
	CAS Number	608-05-9	Molecular Weight	161.157
	Density	1.3±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₉H₇NO₂	Melting Point	180 °C (dec.)(lit.)
	MSDS	USA	Flash Point	N/A

Name	5-Methylisatin
Synonym	More Synonyms

Density	1.3±0.1 g/cm3
Melting Point	180 °C (dec.)(lit.)
Molecular Formula	C₉H₇NO₂
Molecular Weight	161.157
Exact Mass	161.047684
PSA	46.17000
LogP	1.02
Index of Refraction	1.598

5-Methylindoline-2,3-dione MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL7939300

CHEMICAL NAME :: Indole-2,3-dione, 5-methyl-

CAS REGISTRY NUMBER :: 608-05-9

BEILSTEIN REFERENCE NO. :: 0123738

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H7-N-O2

MOLECULAR WEIGHT :: 161.17

WISWESSER LINE NOTATION :: T56 BMVVJ G1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 790 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,858,1981

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NL7939300
HS Code	2933790090

Precursor 9
CAS#:302-17-0 Chloral hydrate CAS#:106-49-0 p-Toluidine CAS#:1132-40-7 (2E)-2-(Hydroxy... CAS#:201230-82-2 carbon monoxide
CAS#:58226-34-9 N'-(2-Bromo-4-m... CAS#:79-37-8 Oxalyl chloride CAS#:5470-11-1 Hydroxyamine hy... CAS#:29650-23-5 5-methyl-indoli...
CAS#:583-68-6 2-Bromo-p-toluidine
DownStream 10
CAS#:108053-80-1 5-methyl-1-[3-(... CAS#:3484-35-3 5-Methoxyindole CAS#:1955-61-9 2,4-Quinazoline... CAS#:1908-01-6 ethyl 5-methyl-...
CAS#:4692-99-3 6-Methyl-isatoi... CAS#:2941-79-9 4,4'-Dimethyl[1... CAS#:2437-73-2 2,3,6-Trimethyl... CAS#:5925-93-9 2-amino-5-methy...
CAS#:13208-98-5 (3-TRIFLUOROMET... CAS#:104175-33-9 2,6-DIMETHYL-QU...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Isatin (indole-2,3-dione) in urine and tissues. Detection and determination by gas chromatography-mass spectrometry.

J. Chromatogr. A. 562(1-2) , 279-87, (1991)

A simple procedure based upon capillary column gas chromatography-mass spectrometry (GC-MS) is described for the detection and determination of isatin (indole-2,3-dione) in body fluids and tissues. Af...

Efficacy of isatin analogues as antagonists of rat brain and heart atrial natriuretic peptide receptors coupled to particulate guanylyl cyclase.

Biochem. Pharmacol. 57(8) , 913-5, (1999)

Isatin is an endogenous indole and an inhibitor of atrial natriuretic peptide (ANP) receptors coupled with particulate guanylyl cyclase (GC). In this study, several isatin analogues were tested as inh...

[The reaction of 3-(R-phenyl)-6-hydrazine pyridazine with 5-methylisatin and 1-morpholinomethyl-5-methylisatin].

Rev. Med. Chir. Soc. Med. Nat. Iasi. 100(1-2) , 167-71, (1996)

This paper presents the synthesis of six hydrazones obtained by treating 5-methyl-isatin or 1-morpholino methyl-5-methyl-isatin with 3-(R-phenyl)-6-hydrazino-pyridazine (R = OCH3, Cl, Br) and two comp...

EINECS 210-152-1

5-Methyl-1H-indole-2,3-dione

5-Methylisatin

1H-Indole-2,3-dione, 5-methyl-

MFCD00005721

5-methylindoline-2,3-dione