Triolein-d5

Modify Date: 2024-01-20 13:23:04

Triolein-d5 Structure
Triolein-d5 structure
Common Name Triolein-d5
CAS Number 60892-83-3 Molecular Weight 890.46
Density 0.9±0.1 g/cm3 Boiling Point 818.7±55.0 °C at 760 mmHg
Molecular Formula C57H99D5O6 Melting Point N/A
MSDS N/A Flash Point 302.7±31.5 °C

 Use of Triolein-d5


Triolein-d5 is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].

 Names

Name Glyceryl-d5 Trioleate
Synonym More Synonyms

 Triolein-d5 Biological Activity

Description Triolein-d5 is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Leirós GJ, et al. Triolein reduces MMP-1 upregulation in dermal fibroblasts generated by ROS production in UVB-irradiated keratinocytes. J Dermatol Sci. 2017 Feb;85(2):124-130.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 818.7±55.0 °C at 760 mmHg
Molecular Formula C57H99D5O6
Molecular Weight 890.46
Flash Point 302.7±31.5 °C
Exact Mass 889.814697
LogP 23.71
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.477

 Synonyms

9-Octadecenoic acid, 1,2,3-propanetriyl-d5 ester, (9Z,9'Z,9''Z)-
(2H5)-1,2,3-Propanetriyl (9Z,9'Z,9''Z)tris(-9-octadecenoate)