CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XI0383750
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CHEMICAL NAME :
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5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-8-oxo-3-(((1-sulfometh yl)-1H-tetrazol-5-yl) thio)methyl)-, (6R-(6-alpha,7-beta(R*)))-
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CAS REGISTRY NUMBER :
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61270-58-4
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C18-H18-N6-O8-S3
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MOLECULAR WEIGHT :
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542.60
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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40 mg/kg/2D-I
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TOXIC EFFECTS :
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Kidney, Ureter, Bladder - hematuria Blood - hemorrhage Blood - tumors
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REFERENCE :
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AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 123,472,1995 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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83 gm/kg/13W-I
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TOXIC EFFECTS :
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Blood - normocytic anemia Blood - thrombocytopenia
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REFERENCE :
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TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 90,143,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5274 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 307 (estimated) No. of Female Employees: 251 (estimated)
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