Isoacteoside

Modify Date: 2024-01-02 19:02:17

Isoacteoside Structure
Isoacteoside structure
Common Name Isoacteoside
CAS Number 61303-13-7 Molecular Weight 624.587
Density 1.6±0.1 g/cm3 Boiling Point 942.9±65.0 °C at 760 mmHg
Molecular Formula C29H36O15 Melting Point 220-230℃
MSDS N/A Flash Point 306.1±27.8 °C

 Use of Isoacteoside


Isoacteoside is a natural compound which exhibit significant inhibition of advanced glycation end product formation with IC50 values of 4.6-25.7 μM, compared with those of aminoguanidine (IC50=1,056 μM) and quercetin (IC50=28.4 μM) as positive controls.IC50 value:Target:In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 μM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 μM) and quercetin (IC50=7.2 μM).

 Names

Name Isoacteoside
Synonym More Synonyms

 Isoacteoside Biological Activity

Description Isoacteoside is a natural compound which exhibit significant inhibition of advanced glycation end product formation with IC50 values of 4.6-25.7 μM, compared with those of aminoguanidine (IC50=1,056 μM) and quercetin (IC50=28.4 μM) as positive controls.IC50 value:Target:In the rat lens aldose reductase assay, acteoside, isoacteoside, and poliumoside exhibited greater inhibitory effects on rat lens aldose reductase with IC50 values of 0.83, 0.83, and 0.85 μM, respectively, than those of the positive controls, 3,3-tetramethyleneglutaric acid (IC50=4.03 μM) and quercetin (IC50=7.2 μM).
Related Catalog
References

[1]. Yu SY, et al. Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo. Planta Med. 2013 Dec;79(18):1705-9.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 942.9±65.0 °C at 760 mmHg
Melting Point 220-230℃
Molecular Formula C29H36O15
Molecular Weight 624.587
Flash Point 306.1±27.8 °C
Exact Mass 624.205444
PSA 245.29000
LogP 2.58
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.689
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synthetic Route

~78%

Isoacteoside Structure

Isoacteoside

CAS#:61303-13-7

Literature: Wong; He; Huang; Chen Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 6 p. 3113 - 3119

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

verbascoside
ISOVERBASCOSIDE
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-β-D-glucopyranoside
Isoacteosid
β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-
iso-Acteoside
β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-β-D-glucopyranoside
isoacetoside
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