N-Nitroso-N-Methyl-4-Aminobutyric Acid

MOLECULAR FORMULA :

C5-H10-N2-O3

MOLECULAR WEIGHT :

146.17

WISWESSER LINE NOTATION :

QV3N1&NO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

6800 mg/kg/57W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Parenteral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4500 mg/kg/30W-I

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

8500 mg/kg/57W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :

Mutation in microorganisms

TEST SYSTEM :

Yeast - Saccharomyces cerevisiae

DOSE/DURATION :

16260 mg/L

REFERENCE :

IAPUDO IARC Publications. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.27- 1979- Volume(issue)/page/year: 57,721,1984