EP2 receptor antagonist-2
Modify Date: 2024-01-31 20:11:43
EP2 receptor antagonist-2 structure
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Common Name | EP2 receptor antagonist-2 | ||
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| CAS Number | 615273-95-5 | Molecular Weight | 309.29 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 451.8±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H14F3N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 227.0±31.5 °C | |
Use of EP2 receptor antagonist-2EP2 receptor antagonist-2 (CID891729) is an antagonist of EP2 receptor. EP2 receptor antagonist-2 inhibits the EP2 receptor activation induced by PGE2. EP2 receptor antagonist-2 also suppresses lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA)[1]. |
| Name | WAY-327111 |
|---|---|
| Synonym | More Synonyms |
| Description | EP2 receptor antagonist-2 (CID891729) is an antagonist of EP2 receptor. EP2 receptor antagonist-2 inhibits the EP2 receptor activation induced by PGE2. EP2 receptor antagonist-2 also suppresses lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA)[1]. |
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| Related Catalog | |
| Target |
EP |
| In Vitro | EP2 receptor antagonist-2 对 C6G 细胞具有细胞毒性，CC50 为 575 μM[1]。 EP2 receptor antagonist-2 (20 μM；30 min) 降低大鼠原代海马神经元 (DIV14) 中 NMDA (30 μM) 诱导的 LDH 释放[1]。 |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 451.8±55.0 °C at 760 mmHg |
| Molecular Formula | C15H14F3N3O |
| Molecular Weight | 309.29 |
| Flash Point | 227.0±31.5 °C |
| Exact Mass | 309.108887 |
| LogP | 3.81 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.533 |
| Morpholine, 4-[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]- |
| 4-(4-Phenyl-6-trifluoromethyl-pyrimidin-2-yl)-morpholine |
| 4-[4-Phenyl-6-(trifluoromethyl)-2-pyrimidinyl]morpholine |