DeMethoxycapillarisin

Modify Date: 2024-01-13 18:19:34

DeMethoxycapillarisin Structure
DeMethoxycapillarisin structure
Common Name DeMethoxycapillarisin
CAS Number 61854-36-2 Molecular Weight 286.236
Density 1.6±0.1 g/cm3 Boiling Point 535.9±50.0 °C at 760 mmHg
Molecular Formula C15H10O6 Melting Point N/A
MSDS N/A Flash Point 207.5±23.6 °C

 Use of DeMethoxycapillarisin


Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1].

 Names

Name 5,7-dihydroxy-2-(4-hydroxyphenoxy)chromen-4-one
Synonym More Synonyms

 DeMethoxycapillarisin Biological Activity

Description Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production[1].
Related Catalog
References

[1]. Govorko D, et al. Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1503-10.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 535.9±50.0 °C at 760 mmHg
Molecular Formula C15H10O6
Molecular Weight 286.236
Flash Point 207.5±23.6 °C
Exact Mass 286.047729
PSA 100.13000
LogP 2.70
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.729

 Safety Information

Hazard Codes Xi

 Synthetic Route

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475

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DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475

~%

DeMethoxycapillarisin Structure

DeMethoxycapill...

CAS#:61854-36-2

Literature: Takeno, Hidekazu; Hashimoto, Masashi; Koma, Yoshiyasu; Horiai, Haruo; Kikuchi, Hiroyuki Journal of the Chemical Society, Chemical Communications, 1981 , # 10 p. 474 - 475

 Synonyms

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenoxy)-
5,7-Dihydroxy-2-(4-hydroxyphenoxy)-4H-chromen-4-one
Demethoxycapillarisin
6-Demethoxycapillarisin
6-demethoxycapilarisin