6-Chlorobenzo[D]Isoxazol-3-Ol
![6-Chlorobenzo[D]Isoxazol-3-Ol Structure](https://image.chemsrc.com/caspic/066/61977-29-5.png)
6-Chlorobenzo[D]Isoxazol-3-Ol structure
|
Common Name | 6-Chlorobenzo[D]Isoxazol-3-Ol | ||
|---|---|---|---|---|
| CAS Number | 61977-29-5 | Molecular Weight | 169.565 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 336.7±22.0 °C at 760 mmHg | |
| Molecular Formula | C7H4ClNO2 | Melting Point | 218-220ºC | |
| MSDS | Chinese USA | Flash Point | 157.4±22.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 6-Chlorobenzo[D]Isoxazol-3-OlCBIO is a potent, cell-permeable, D-amino acid oxidase (DAO) reversible inhibitor. In rat models, CBIO prevents formalin-induced tonic pain but not acute nociception. |
| Name | 6-Chlorobenzo[d]isoxazol-3-ol |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 336.7±22.0 °C at 760 mmHg |
| Melting Point | 218-220ºC |
| Molecular Formula | C7H4ClNO2 |
| Molecular Weight | 169.565 |
| Flash Point | 157.4±22.3 °C |
| Exact Mass | 168.993057 |
| PSA | 46.26000 |
| LogP | 1.49 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.674 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2934999090 |
|
~88%
6-Chlorobenzo[D... CAS#:61977-29-5 |
| Literature: Jiangsu Guohua Investment Co., Ltd; Shanghai Institute of Pharmaceutical Industry Patent: EP2322520 A1, 2011 ; Location in patent: Page/Page column 12 ; |
|
~%
6-Chlorobenzo[D... CAS#:61977-29-5 |
| Literature: US5484763 A1, ; |
|
~%
6-Chlorobenzo[D... CAS#:61977-29-5 |
| Literature: EP2322520 A1, ; |
|
~%
6-Chlorobenzo[D... CAS#:61977-29-5 |
| Literature: EP2322520 A1, ; |
![(5,6-DIMETHYL-4-OXO-3,4-DIHYDRO-THIENO[2,3-D]PYRIMIDIN-2-YL)-ACETICACIDMETHYLESTER structure](https://image.chemsrc.com/caspic/353/61799-78-8.png)
![3,6-Dichlorobenzo[d]isoxazole structure](https://image.chemsrc.com/caspic/189/16263-54-0.png)
CAS#:16263-54-0| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|
Salmonella evades D-amino acid oxidase to promote infection in neutrophils.
MBio 5(6) , e01886, (2014) Neutrophils engulf and kill bacteria using oxidative and nonoxidative mechanisms. Despite robust antimicrobial activity, neutrophils are impaired in directing Salmonella clearance and harbor viable in... |
|
|
Contributions of spinal D-amino acid oxidase to chronic morphine-induced hyperalgesia.
J. Pharm. Biomed. Anal. 116 , 131-8, (2015) Spinal D-amino acid oxidase (DAAO) is an FAD-dependent peroxisomal flavoenzyme which mediates the conversion of neutral and polar D-amino acids (including D-serine) to the corresponding α-keto acids, ... |
| 6-Chloro-1,2-benzoxazol-3(2H)-one |
| 1,2-Benzisoxazol-3(2H)-one, 6-chloro- |
| 6-chloro-1,2-benzoxazol-3-one |
| 6-Chlorobenzo[D]Isoxazol-3-Ol |