5-Acetyl-8-hydroxy-2(1H)-quinolinone

Modify Date: 2024-01-06 18:18:25

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure
5-Acetyl-8-hydroxy-2(1H)-quinolinone structure
Common Name 5-Acetyl-8-hydroxy-2(1H)-quinolinone
CAS Number 62978-73-8 Molecular Weight 203.194
Density 1.3±0.1 g/cm3 Boiling Point 509.5±50.0 °C at 760 mmHg
Molecular Formula C11H9NO3 Melting Point >260ºC
MSDS USA Flash Point 261.9±30.1 °C

 Names

Name 5-acetyl-8-hydroxy-1h-quinolin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 509.5±50.0 °C at 760 mmHg
Melting Point >260ºC
Molecular Formula C11H9NO3
Molecular Weight 203.194
Flash Point 261.9±30.1 °C
Exact Mass 203.058243
PSA 70.42000
LogP 1.42
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.620
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2933790090

 Synthetic Route

~%

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: US2004/167167 A1, ; Page/Page column 32 ; US 20040167167 A1

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5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: US2004/224982 A1, ; Page 9-10 ;

~80%

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2005/123684 A2, 2005 ; Location in patent: Page/Page column 33-34 ;

~93%

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: Amlaiky; Leclerc; Decker; Schwartz European Journal of Medicinal Chemistry, 1984 , vol. 19, # 4 p. 341 - 346

~31%

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2005/123684 A2, 2005 ; Location in patent: Page/Page column 32-33 ;

~%

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: European Journal of Medicinal Chemistry, , vol. 19, # 4 p. 341 - 346

~%

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: European Journal of Medicinal Chemistry, , vol. 19, # 4 p. 341 - 346

~%

5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: US2012/46467 A1, ;

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5-Acetyl-8-hydroxy-2(1H)-quinolinone Structure

5-Acetyl-8-hydr...

CAS#:62978-73-8

Literature: US2012/46467 A1, ;

 Customs

HS Code 2933790090
Summary 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

 Synonyms

5-Acetyl-quinoline-2,8-diol
5-acetyl-8-hydroxycarbostyril
acetylhydroxydihydroquinolinone
acetyl-5 hydroxy-8 carbostyrile
2(1H)-Quinolinone, 5-acetyl-8-hydroxy-
5-acetyl-8-hydroxy-(1H)-quinolin-2-one
5-Acetyl-8-hydroxy-2(1H)-quinolinone
5-Acetyl-8-hydroxyquinolin-2(1H)-one
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