2-Thiophenesulfonamide

Modify Date: 2024-01-08 09:59:56

2-Thiophenesulfonamide Structure
2-Thiophenesulfonamide structure
Common Name 2-Thiophenesulfonamide
CAS Number 6339-87-3 Molecular Weight 163.218
Density 1.5±0.1 g/cm3 Boiling Point 338.1±34.0 °C at 760 mmHg
Molecular Formula C4H5NO2S2 Melting Point 146-148ºC
MSDS Chinese USA Flash Point 158.3±25.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Thiophenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 338.1±34.0 °C at 760 mmHg
Melting Point 146-148ºC
Molecular Formula C4H5NO2S2
Molecular Weight 163.218
Flash Point 158.3±25.7 °C
Exact Mass 162.976166
PSA 96.78000
LogP -0.08
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.609

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XN0294000
CHEMICAL NAME :
2-Thiophenesulfonamide
CAS REGISTRY NUMBER :
6339-87-3
BEILSTEIN REFERENCE NO. :
0123537
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C4-H5-N-O2-S2
MOLECULAR WEIGHT :
163.22
WISWESSER LINE NOTATION :
T5SJ BSWZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 19,449,1961

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
RTECS XN0294000
HS Code 2935009090

 Synthetic Route

~76%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: ISIS INNOVATION LIMITED; RUSSELL, Angela, Jane; SIM, Edith; DAVIES, Steven, Graham; WESTWOOD, Isaac, Mark; KAWAMURA, Akane; CRAWFORD, Matthew, Howard, James; LAURIERI, Nicola Patent: WO2011/55142 A2, 2011 ; Location in patent: Page/Page column 47 ; WO 2011/055142 A2

~98%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: Wan, Yiqian; Wu, Xiongyu; Kannan, Mahalingam A.; Alterman, Mathias Tetrahedron Letters, 2003 , vol. 44, # 24 p. 4523 - 4525

~87%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: Obafemi, Craig. A.; Onigbinde, Adebayo O. Phosphorus, Sulfur and Silicon and the Related Elements, 1991 , vol. 57, # 1/2 p. 75 - 81

~%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: US2004/48802 A1, ; US 20040048802 A1

~81%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: Obafemi, Craig A. Phosphorus and Sulfur and the Related Elements, 1980 , vol. 8, p. 197 - 200

~%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: Journal of Organic Chemistry, , vol. 58, # 25 p. 7022 - 7028

~%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: Synthesis, , vol. No. 12, p. 1031 - 1032

~%

2-Thiophenesulfonamide Structure

2-Thiophenesulf...

CAS#:6339-87-3

Literature: Tetrahedron Letters, , vol. 35, # 39 p. 7201 - 7204

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

Thiophene-2-sulfonic acid amide
2-Thiophenesulfonamide
Thiophene-2-sulfonamide
MFCD00185853
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