Oxonol VI

Modify Date: 2024-01-02 19:36:27

Oxonol VI Structure
Oxonol VI structure
Common Name Oxonol VI
CAS Number 64724-75-0 Molecular Weight 316.35200
Density 1.19g/cm3 Boiling Point 381.4ºC at 760 mmHg
Molecular Formula C17H20N2O4 Melting Point N/A
MSDS Chinese USA Flash Point 184.5ºC

 Use of Oxonol VI


Oxonol VI acts as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is suitable for detecting changes of membrane potential associated with the activity of the (Na+ + K+)-ATPase in reconstituted vesicles[1].

 Names

Name (4Z)-4-[(2E,4E)-5-(5-oxo-3-propyl-2H-1,2-oxazol-4-yl)penta-2,4-dienylidene]-3-propyl-1,2-oxazol-5-one
Synonym More Synonyms

 Oxonol VI Biological Activity

Description Oxonol VI acts as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is suitable for detecting changes of membrane potential associated with the activity of the (Na+ + K+)-ATPase in reconstituted vesicles[1].
Related Catalog
References

[1]. H J Apell, et al. Oxonol VI as an optical indicator for membrane potentials in lipid vesicles. Biochim Biophys Acta. 1987 Oct 16;903(3):480-94.

 Chemical & Physical Properties

Density 1.19g/cm3
Boiling Point 381.4ºC at 760 mmHg
Molecular Formula C17H20N2O4
Molecular Weight 316.35200
Flash Point 184.5ºC
Exact Mass 316.14200
PSA 84.92000
LogP 2.97700
Index of Refraction 1.563

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport

 Articles26

More Articles
Conserved amino acid residues of the NuoD segment important for structure and function of Escherichia coli NDH-1 (complex I).

Biochemistry 54(3) , 753-64, (2015)

The NuoD segment (homologue of mitochondrial 49 kDa subunit) of the proton-translocating NADH:quinone oxidoreductase (complex I/NDH-1) from Escherichia coli is in the hydrophilic domain and bears many...

ATP-dependent spectral response of oxonol VI in an ATP-Pi exchange complex.

Biochim. Biophys. Acta 766(2) , 375-85, (1984)

Energy transduction in an ATPase complex (complex V) has been studied in two reactions catalyzed by this system, i.e., ATP-dependent spectral shift of oxonol VI, and ATP-Pi exchange activity. Aurovert...

Effects of Cd2+ on ATP-driven membrane potential in beef heart mitochondrial H+-ATPase: a study using the voltage-sensitive probe oxonol VI.

Membr. Biochem. 5(3) , 225-41, (1984)

Beef heart mitochondrial H+-ATPase (F1-F0) vesicles were prepared by lysolecithin extraction of ETPH. ATP-driven membrane potential was monitored indirectly by following absorbance changes of the pote...

 Synonyms

oxonol VI
Bis(3-propyl-5-oxoisoxazol-4-yl)pentamethine oxanol
MFCD00210076
5(4H)-Isoxazolone,4-(5-(5-hydroxy-3-propyl-4-isoxazolyl)-2,4-pentadienylidene)-3-propyl
Oxanol VI
Bis(3-propyl-5-oxoisoxazol-4-yl)pentamethineoxonol