Pyrimidinone 8
Modify Date: 2024-01-05 18:29:44
Pyrimidinone 8 structure
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Common Name | Pyrimidinone 8 | ||
|---|---|---|---|---|
| CAS Number | 65004-42-4 | Molecular Weight | 204.229 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 410.4±48.0 °C at 760 mmHg | |
| Molecular Formula | C10H12N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 202.0±29.6 °C | |
Use of Pyrimidinone 8Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM; does not affect hDMT1 cell surface expression and shows no dependence on extracellular pH. |
| Name | 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-ol |
|---|---|
| Synonym | More Synonyms |
| Description | Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM; does not affect hDMT1 cell surface expression and shows no dependence on extracellular pH. |
|---|---|
| References | References 1. Montalbetti N, et al. Biochem Pharmacol. 2015 Aug 1;96(3):216-24. View Related Products by Target Other Targets |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 410.4±48.0 °C at 760 mmHg |
| Molecular Formula | C10H12N4O |
| Molecular Weight | 204.229 |
| Flash Point | 202.0±29.6 °C |
| Exact Mass | 204.101105 |
| LogP | 1.28 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.650 |
| 4(1H)-Pyrimidinone, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl- |
| 4(3H)-pyrimidinone, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methyl- |
| MFCD01416214 |
| 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one |
| 2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-methyl-4(1H)-pyrimidinone |
| MFCD00097142 |
| 2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4-ol |