1,3-Propanediamine,N1,N1-diethyl-N3-(6-methyl-5H-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolin-10-yl)-

Modify Date: 2024-01-06 18:38:46

1,3-Propanediamine,N1,N1-diethyl-N3-(6-methyl-5H-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolin-10-yl)- structure	Common Name	1,3-Propanediamine,N1,N1-diethyl-N3-(6-methyl-5H-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolin-10-yl)-
	CAS Number	65222-35-7	Molecular Weight	361.48300
	Density	1.21g/cm3	Boiling Point	615.2ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₇N₅	Melting Point	N/A
	MSDS	N/A	Flash Point	325.9ºC

Name	Pazelliptine
Synonym	More Synonyms

Density	1.21g/cm3
Boiling Point	615.2ºC at 760 mmHg
Molecular Formula	C₂₂H₂₇N₅
Molecular Weight	361.48300
Flash Point	325.9ºC
Exact Mass	361.22700
PSA	56.84000
LogP	4.78950
Index of Refraction	1.707

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX7388500

CAS REGISTRY NUMBER :: 65222-35-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C22-H27-N5

MOLECULAR WEIGHT :: 361.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 17 umol/L

REFERENCE :: BUCABS Bulletin du Cancer. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53- 1966- Volume(issue)/page/year: 67,9,1980

pyrrolo[2,3-g]i...

CAS#:58832-85-2

1,1-diethyl-2-p...

CAS#:67398-38-3

~76%

1,3-Propanediam...

CAS#:65222-35-7

Literature: Sanofi Patent: US5079363 A1, 1992 ;

N/A

CAS#:148729-96-8

N,N-Diethylprop...

CAS#:104-78-9

~87%

1,3-Propanediam...

CAS#:65222-35-7

Literature: Dormoy; Heymes Tetrahedron, 1993 , vol. 49, # 14 p. 2915 - 2938

N/A

CAS#:148729-96-8

1,3-Propanediam...

CAS#:65222-35-7

Literature: Dormoy; Heymes Tetrahedron, 1993 , vol. 49, # 14 p. 2915 - 2938

10-Chloro-6-met...

CAS#:69022-46-4

N,N-Diethylprop...

CAS#:104-78-9

~84%

1,3-Propanediam...

CAS#:65222-35-7

Literature: Dormoy; Heymes Tetrahedron, 1993 , vol. 49, # 14 p. 2915 - 2938

Precursor 3
CAS#:58832-85-2 pyrrolo[2,3-g]i... CAS#:67398-38-3 1,1-diethyl-2-p... CAS#:104-78-9 N,N-Diethylprop...
DownStream 0

Pazeliptina [Spanish]

EINECS 265-640-7

N,N-diethyl-N'-(6-methyl-5H-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinoline-10-yl)-propane-1,3-diamine

n,n-diethyl-n'-(6-methyl-5h-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolin-10-yl)propane-1,3-diamine

10-<<3-(diethylamino)propyl>amino>-6-methyl-5H-pyrido<3',4':4,5>pyrrolo<2,3-g>isoquinoline

BD-40

Pazelliptinum [Latin]

1,3-Propanediamine,N1,N1-diethyl-N3-(6-methyl-5H-pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolin-10-yl)-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Synthetic Route

Precursor & DownStream

Synonyms