2,4,6-Trichlorobenzonitrile

Modify Date: 2024-01-02 10:28:50

2,4,6-Trichlorobenzonitrile Structure
2,4,6-Trichlorobenzonitrile structure
Common Name 2,4,6-Trichlorobenzonitrile
CAS Number 6575-05-9 Molecular Weight 206.456
Density 1.5±0.1 g/cm3 Boiling Point 303.1±37.0 °C at 760 mmHg
Molecular Formula C7H2Cl3N Melting Point 80-82°C
MSDS N/A Flash Point 136.4±20.7 °C

 Names

Name 2,4,6-Trichlorobenzonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 303.1±37.0 °C at 760 mmHg
Melting Point 80-82°C
Molecular Formula C7H2Cl3N
Molecular Weight 206.456
Flash Point 136.4±20.7 °C
Exact Mass 204.925278
PSA 23.79000
LogP 3.36
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.601

 MSDS

2,4,6-Trichlorobenzonitrile
SAFETY DATA SHEET

Section1. IDENTIFICATION
Product name:2,4,6-Trichlorobenzonitrile

Section2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDSNot classified
HEALTH HAZARDS
Acute toxicity (Oral)Category 4
Category 4
Acute toxicity (Dermal)
Acute toxicity (Inhalation)Category 4
Category 2
Skin corrosion/irritation
Serious eye damage/eye irritationCategory 2A
Not classified
ENVIRONMENTAL HAZARDS
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Signal wordWarning
Harmful if swallowed, in contact with skin or if inhaled
Hazard statements
Causes skin irritation
Causes serious eye irritation
Precautionary statements:
Avoid breathing dust/fume/gas/mist/vapours/spray.
[Prevention]
Use only outdoors or in a well-ventilated area.
Do not eat, drink or smoke when using this product.
Wash hands thoroughly after handling.
Wear protective gloves and eye/face protection.
[Response]IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for
breathing. Call a POISON CENTER or doctor/physician if you feel unwell.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Rinse mouth.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Wash contaminated clothing before reuse.
Call a POISON CENTER or doctor/physician if you feel unwell.
2,4,6-Trichlorobenzonitrile

Section2. HAZARDS IDENTIFICATION
[Disposal]Dispose of contents/container through a waste management company authorized by
the local government.

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture:Substance
Components:2,4,6-Trichlorobenzonitrile
>97.0%(GC)
Percent:
CAS Number:6575-05-9
Chemical Formula:C7H2Cl3N

Section4. FIRST AID MEASURES
Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Call a POISON CENTER or doctor/physician if you feel unwell.
Skin contact:Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Rinse cautiously with water for several minutes. Remove contact lenses, if present
Eye contact:
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion:Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Suitable extinguishingDry chemical, foam, water spray, carbon dioxide.
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
from the chemical:
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak.
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Handling is performed in a well ventilated place. Wear suitable protective equipment.
Technical measures:
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Keep container tightly closed. Store in a cool and dark place.
Storage conditions:
Store locked up.
Store away from incompatible materials such as oxidizing agents.
Packaging material:Comply with laws.
2,4,6-Trichlorobenzonitrile

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering controls:Install a closed system or local exhaust as possible so that workers should not be
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator, self-contained breathing apparatus(SCBA), supplied air respirator,
etc. Use respirators approved under appropriate government standards and follow
local and national regulations.
Hand protection:Impervious gloves.
Safety goggles. A face-shield, if the situation requires.
Eye protection:
Skin and body protection: Impervious protective clothing. Protective boots, if the situation requires.

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Solid
Crystal- Powder
Form:
Colour:White - Slightly pale reddish yellow
No data available
Odour:
pH: No data available
Melting point/freezing point:79°C
Boiling point/range:No data available
Flash point:No data available
Flammability or explosive
limits:
Lower:No data available
Upper:No data available
Relative density:No data available
Solubility(ies):
[Water]No data available
[Other solvents]
Soluble:Toluene

Section10. STABILITY AND REACTIVITY
Chemical stability:Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen chloride
products:

Section11. TOXICOLOGICAL INFORMATION
Acute Toxicity:No data available
Skin corrosion/irritation: No data available
Serious eyeNo data available
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
IARC =No data available
NTP =No data available
Reproductive toxicity:No data available

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish:No data available
Crustacea:No data available
No data available
Algae:
Persistence / degradability: No data available
No data available
Bioaccumulative
potential(BCF):
2,4,6-Trichlorobenzonitrile

Section12. ECOLOGICAL INFORMATION
Mobility in soil
No data available
Log Pow:
Soil adsorption (Koc):No data available
No data available
Henry's Law
constant(PaM3/mol):

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

Section14. TRANSPORT INFORMATION
Does not correspond to the classification standard of the United Nations
Hazards Class:
UN-No:Not listed

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
RIDADR 3276
Packaging Group III
Hazard Class 6.1
HS Code 2926909090

 Synthetic Route

~85%

2,4,6-Trichlorobenzonitrile Structure

2,4,6-Trichloro...

CAS#:6575-05-9

Literature: ELI LILLY AND COMPANY Patent: WO2006/44454 A1, 2006 ; Location in patent: Page/Page column 73-74 ; WO 2006/044454 A1

~%

2,4,6-Trichlorobenzonitrile Structure

2,4,6-Trichloro...

CAS#:6575-05-9

Literature: Journal of the American Chemical Society, , vol. 62, p. 1432,1434

~80%

2,4,6-Trichlorobenzonitrile Structure

2,4,6-Trichloro...

CAS#:6575-05-9

Literature: Rezaei, Ramin; Karami, Marzeih Chinese Chemical Letters, 2011 , vol. 22, # 7 p. 815 - 818

~%

2,4,6-Trichlorobenzonitrile Structure

2,4,6-Trichloro...

CAS#:6575-05-9

Literature: US4530797 A1, ;

~%

2,4,6-Trichlorobenzonitrile Structure

2,4,6-Trichloro...

CAS#:6575-05-9

Literature: Chemische Berichte, , vol. 27, p. 3151

~%

2,4,6-Trichlorobenzonitrile Structure

2,4,6-Trichloro...

CAS#:6575-05-9

Literature: Chemische Berichte, , vol. 27, p. 3151

~%

2,4,6-Trichlorobenzonitrile Structure

2,4,6-Trichloro...

CAS#:6575-05-9

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 21, p. 384 Journal of the Chemical Society, , vol. 71, p. 231 Chemische Berichte, , vol. 27, p. 3152

 Customs

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

Benzonitrile, 2,4,6-trichloro-
2,4,6-trichloro-benzonitrile
MFCD00052711
2,4,6-Trichlorobenzonitrile
2.4.6-Trichlor-benzonitril
2,4,6-trichlorobenzenecarbonitrile
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