1,5-Difluoro-3-methoxy-2-nitrobenzene

Modify Date: 2024-01-08 14:53:11

1,5-Difluoro-3-methoxy-2-nitrobenzene Structure
1,5-Difluoro-3-methoxy-2-nitrobenzene structure
Common Name 1,5-Difluoro-3-methoxy-2-nitrobenzene
CAS Number 66684-61-5 Molecular Weight 189.116
Density 1.4±0.1 g/cm3 Boiling Point 237.6±35.0 °C at 760 mmHg
Molecular Formula C7H5F2NO3 Melting Point N/A
MSDS N/A Flash Point 97.5±25.9 °C

 Names

Name 1,5-Difluoro-3-Methoxy-2-Nitro-Benzene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 237.6±35.0 °C at 760 mmHg
Molecular Formula C7H5F2NO3
Molecular Weight 189.116
Flash Point 97.5±25.9 °C
Exact Mass 189.023743
PSA 55.05000
LogP 1.46
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.502

 Safety Information

HS Code 2909309090

 Synthetic Route

~85%

1,5-Difluoro-3-methoxy-2-nitrobenzene Structure

1,5-Difluoro-3-...

CAS#:66684-61-5

Literature: DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1346982 A1, 2003 ;

~72%

1,5-Difluoro-3-methoxy-2-nitrobenzene Structure

1,5-Difluoro-3-...

CAS#:66684-61-5

Literature: Malamas, Michael S.; Ni, Yike; Erdei, James; Stange, Hans; Schindler, Rudolf; Lankau, Hans-Joachim; Grunwald, Christian; Fan, Kristi Yi; Parris, Kevin; Langen, Barbara; Egerland, Ute; Hage, Thorsten; Marquis, Karen L.; Grauer, Steve; Brennan, Julie; Navarra, Rachel; Graf, Radka; Harrison, Boyd L.; Robichaud, Albert; Kronbach, Thomas; Pangalos, Menelas N.; Hoefgen, Norbert; Brandon, Nicholas J. Journal of Medicinal Chemistry, 2011 , vol. 54, # 21 p. 7621 - 7638

~93%

1,5-Difluoro-3-methoxy-2-nitrobenzene Structure

1,5-Difluoro-3-...

CAS#:66684-61-5

Literature: SANOFI Patent: US2012/277220 A1, 2012 ; Location in patent: Page/Page column 19 ;

~%

1,5-Difluoro-3-methoxy-2-nitrobenzene Structure

1,5-Difluoro-3-...

CAS#:66684-61-5

Literature: Barnard; Storr; O'Neill; Park Journal of Pharmacy and Pharmacology, 1993 , vol. 45, # 8 p. 736 - 744

~%

1,5-Difluoro-3-methoxy-2-nitrobenzene Structure

1,5-Difluoro-3-...

CAS#:66684-61-5

Literature: Journal of Medicinal Chemistry, , vol. 37, # 9 p. 1362 - 1370

~%

1,5-Difluoro-3-methoxy-2-nitrobenzene Structure

1,5-Difluoro-3-...

CAS#:66684-61-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 18 p. 5876 - 5884,9

 Customs

HS Code 2909309090
Summary 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

3,5-Difluoro-2-nitrophenyl methyl ether
1,5-Difluoro-3-methoxy-2-nitrobenzene
Benzene, 1,5-difluoro-3-methoxy-2-nitro-