CID3528206

Modify Date: 2024-10-06 13:49:44

CID3528206 Structure
CID3528206 structure
Common Name CID3528206
CAS Number 674359-78-5 Molecular Weight 278.242
Density 1.5±0.1 g/cm3 Boiling Point 493.9±55.0 °C at 760 mmHg
Molecular Formula C11H11FN6O2 Melting Point N/A
MSDS N/A Flash Point 252.5±31.5 °C

 Use of CID3528206


CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively; alters GFP expression in all five GFP clones in a manner analogous to that of rapamycin, inhibits yeast cell growth.

 Names

Name N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine
Synonym More Synonyms

 CID3528206 Biological Activity

Description CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively; alters GFP expression in all five GFP clones in a manner analogous to that of rapamycin, inhibits yeast cell growth.
References References 1. Chen J, et al. ACS Chem Biol. 2012 Apr 20;7(4):715-22. View Related Products by Target mTOR

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 493.9±55.0 °C at 760 mmHg
Molecular Formula C11H11FN6O2
Molecular Weight 278.242
Flash Point 252.5±31.5 °C
Exact Mass 278.092743
LogP 1.91
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.736

 Synonyms

N4-(3-Fluorophenyl)-N2-methyl-5-nitro-2,4,6-pyrimidinetriamine
N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine
2,4,6-Pyrimidinetriamine, N4-(3-fluorophenyl)-N2-methyl-5-nitro-