(2S)-6-Prenylnaringenin
Modify Date: 2024-01-08 19:16:54
(2S)-6-Prenylnaringenin structure
|
Common Name | (2S)-6-Prenylnaringenin | ||
|---|---|---|---|---|
| CAS Number | 68236-13-5 | Molecular Weight | 340.37000 | |
| Density | 1.314±0.06 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H20O5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of (2S)-6-Prenylnaringenin(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1]. |
| Name | 6-prenylnaringenin |
|---|---|
| Synonym | More Synonyms |
| Description | (2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1]. |
|---|---|
| Related Catalog | |
| In Vitro | (2S)-6-Prenylnaringenin (6-Prenylnaringenin) displays a modulatory activity at low micromolar concentrations. (2S)-6-Prenylnaringenin potentiates GABA-induced displacement of [3H]EBOB binding in a concentration-dependent manner where the IC50 value for this potentiation in native GABAA receptors is 3.7 μM, respectively[1]. |
| References |
| Density | 1.314±0.06 g/cm3 |
|---|---|
| Molecular Formula | C20H20O5 |
| Molecular Weight | 340.37000 |
| Exact Mass | 340.13100 |
| PSA | 86.99000 |
| LogP | 4.01860 |
| Storage condition | 2-8°C |
| Water Solubility | Insuluble (9.2E-3 g/L) (25 ºC) |
| RIDADR | NONH for all modes of transport |
|---|
|
Involvement of a Hydrophobic Pocket and Helix 11 in Determining the Modes of Action of Prenylated Flavonoids and Isoflavonoids in the Human Estrogen Receptor.
ChemBioChem. 16 , 2668-77, (2016) Six prenylated (iso)flavonoids were purified from a licorice root extract and subjected to competition experiments with six commercially available (iso)flavonoids. The agonistic and antagonistic activ... |
| YS03 |
| 6-Prenylnaringenin |
| 5,7,4'-Trihydroxy-6-prenylflavanone |
| (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one |