1-ethoxy-2,3-dihydro-1λ5-phosphole 1-oxide

MOLECULAR FORMULA :

C6-H11-O2-P

MOLECULAR WEIGHT :

146.14

WISWESSER LINE NOTATION :

T5P BUTJ AO2 AO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4200 mg/kg

TOXIC EFFECTS :

Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - reactivates cholinesterase

REFERENCE :

PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 7,703,1973