6-Methylnicotinamide

Modify Date: 2024-01-08 10:18:09

6-Methylnicotinamide Structure
6-Methylnicotinamide structure
Common Name 6-Methylnicotinamide
CAS Number 6960-22-1 Molecular Weight 136.151
Density 1.2±0.1 g/cm3 Boiling Point 289.4±28.0 °C at 760 mmHg
Molecular Formula C7H8N2O Melting Point 197-199 °C(lit.)
MSDS Chinese USA Flash Point 128.8±24.0 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 6-Methylnicotinamide


6-Methylnicotinamide, a derivate of nicotinamide, is an endogenous metabolite. A sudden increase of 6-methylnicotinamide in the acute stages of intracerebral hemorrhage (ICH) exacerbates neurological damages[1].

 Names

Name 6-Methylnicotinamide
Synonym More Synonyms

 6-Methylnicotinamide Biological Activity

Description 6-Methylnicotinamide, a derivate of nicotinamide, is an endogenous metabolite. A sudden increase of 6-methylnicotinamide in the acute stages of intracerebral hemorrhage (ICH) exacerbates neurological damages[1].
Related Catalog
References

[1]. En Hu, et al. Temporal metabolomic alteration in rat brains of experimental intracerebral hemorrhage. Brain Res Bull. 2021 May;170:234-245.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 289.4±28.0 °C at 760 mmHg
Melting Point 197-199 °C(lit.)
Molecular Formula C7H8N2O
Molecular Weight 136.151
Flash Point 128.8±24.0 °C
Exact Mass 136.063660
PSA 55.98000
LogP 0.35
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.561

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Synthetic Route

~90%

6-Methylnicotinamide Structure

6-Methylnicotinamide

CAS#:6960-22-1

Literature: Moltzen; Pedersen; Bogeso; Meier; Frederiksen; Sanchez; Lembol Journal of Medicinal Chemistry, 1994 , vol. 37, # 24 p. 4085 - 4099

~74%

6-Methylnicotinamide Structure

6-Methylnicotinamide

CAS#:6960-22-1

Literature: Bossaerts, Jan D.; Dommisse, Roger A.; Alderweireldt, Frank C.; Geerlings, Paul Journal of Chemical Research, Miniprint, 1987 , # 9 p. 2360 - 2384

~%

6-Methylnicotinamide Structure

6-Methylnicotinamide

CAS#:6960-22-1

Literature: Journal of Chemical Research, Miniprint, , # 9 p. 2360 - 2384

~22%

6-Methylnicotinamide Structure

6-Methylnicotinamide

CAS#:6960-22-1

Detail
Literature: Bulletin of the Chemical Society of Japan, , vol. 61, # 8 p. 2837 - 2846

~%

6-Methylnicotinamide Structure

6-Methylnicotinamide

CAS#:6960-22-1

Literature: Journal of Chemical Research, Miniprint, , # 9 p. 2360 - 2384

~%

6-Methylnicotinamide Structure

6-Methylnicotinamide

CAS#:6960-22-1

Literature: Bulletin of the Chemical Society of Japan, , vol. 55, # 9 p. 3055 - 3056

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
Nicotinamide derivatives and mitochondrial respiration.

Biochem. Soc. Trans. 24(1) , 61S, (1996)

 Synonyms

3-Pyridinecarboxamide, 6-methyl-
6-methylpyridine-3-carboxamide
MFCD00006342
6-Methylnicotinamide
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