NPD8733

Modify Date: 2024-09-19 11:39:49

NPD8733 Structure
NPD8733 structure
Common Name NPD8733
CAS Number 696655-62-6 Molecular Weight 309.316
Density 1.3±0.1 g/cm3 Boiling Point 567.0±45.0 °C at 760 mmHg
Molecular Formula C18H15NO4 Melting Point N/A
MSDS N/A Flash Point 296.7±28.7 °C

 Use of NPD8733


NPD8733 (NPD-8733) is a small-molecule ligand of valosin-containing protein (VCP)/p97, binds to the D1 domain of VCP/p97; suppresses the enhanced migration of NIH3T3 cells co-cultured with MCF7 cells using a wound healing co-culture assay.

 Names

Name N-[2-(4-Methoxybenzoyl)-1-benzofuran-3-yl]acetamide
Synonym More Synonyms

 NPD8733 Biological Activity

Description NPD8733 (NPD-8733) is a small-molecule ligand of valosin-containing protein (VCP)/p97, binds to the D1 domain of VCP/p97; suppresses the enhanced migration of NIH3T3 cells co-cultured with MCF7 cells using a wound healing co-culture assay.
References References 1. Suvarna K, et al. J Biol Chem. 2019 Jan 4. pii: jbc.RA118.004741. View Related Products by Target p97/VCP

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 567.0±45.0 °C at 760 mmHg
Molecular Formula C18H15NO4
Molecular Weight 309.316
Flash Point 296.7±28.7 °C
Exact Mass 309.100098
LogP 3.30
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.641

 Synonyms

Acetamide, N-[2-(4-methoxybenzoyl)-3-benzofuranyl]-
N-[2-(4-Methoxybenzoyl)-1-benzofuran-3-yl]acetamide