3-Iodo-L-tyrosine

Modify Date: 2024-01-02 13:54:22

3-Iodo-L-tyrosine Structure
3-Iodo-L-tyrosine structure
Common Name 3-Iodo-L-tyrosine
CAS Number 70-78-0 Molecular Weight 307.085
Density 1.9±0.1 g/cm3 Boiling Point 391.0±42.0 °C at 760 mmHg
Molecular Formula C9H10INO3 Melting Point 210 °C (dec.)(lit.)
MSDS USA Flash Point 190.3±27.9 °C

 Use of 3-Iodo-L-tyrosine


H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor.

 Names

Name 3-iodo-L-tyrosine
Synonym More Synonyms

 3-Iodo-L-tyrosine Biological Activity

Description H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%[1].
References

[1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 391.0±42.0 °C at 760 mmHg
Melting Point 210 °C (dec.)(lit.)
Molecular Formula C9H10INO3
Molecular Weight 307.085
Flash Point 190.3±27.9 °C
Exact Mass 306.970520
PSA 83.55000
LogP 1.54
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.689
Storage condition 2-8°C
Water Solubility dilute aqueous acid: soluble

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2922509090

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

3-Iodotyrosine
EINECS 200-744-8
3-IODO-L-TYROSINE
MFCD00002608
Monoiodotyrosine
3-Monoiodo-L-tyrosine
Tyrosine, 3-iodo-, L-
Tyrosine, 3-iodo-
H-Tyr(3-I)-OH
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