(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione

Modify Date: 2024-01-09 17:25:34

(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione Structure
(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione structure
Common Name (S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione
CAS Number 70058-19-4 Molecular Weight 205.21000
Density 1.348 Boiling Point 357ºC
Molecular Formula C11H11NO3 Melting Point 79-82ºC
MSDS N/A Flash Point 170ºC

 Names

Name 2-[(1s)-2-hydroxy-1-methylethyl]-1h-isoindole-1,3(2h)-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.348
Boiling Point 357ºC
Melting Point 79-82ºC
Molecular Formula C11H11NO3
Molecular Weight 205.21000
Flash Point 170ºC
Exact Mass 205.07400
PSA 57.61000
LogP 0.60130
Storage condition 2-8°C

 Synthetic Route

~99%

(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione Structure

(S)-2-(1-Hydrox...

CAS#:70058-19-4

Literature: ELI LILLY AND COMPANY; COATES, David, Andrew; GILMOUR, Raymond; MARTIN, Jose, Alfredo; MARTIN DE LA NAVA, Eva, Maria Patent: WO2012/74761 A1, 2012 ; Location in patent: Page/Page column 17-18 ;

~99%

(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione Structure

(S)-2-(1-Hydrox...

CAS#:70058-19-4

Literature: Casara, Patrick; Danzin, Charles; Metcalf, Brian; Jung, Michel Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2201 - 2208

~87%

(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione Structure

(S)-2-(1-Hydrox...

CAS#:70058-19-4

Literature: Nisshin Flour Milling Co., Ltd. Patent: US4659833 A1, 1987 ; US 4659833 A

~%

(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione Structure

(S)-2-(1-Hydrox...

CAS#:70058-19-4

Literature: Casara, Patrick; Danzin, Charles; Metcalf, Brian; Jung, Michel Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2201 - 2208

~74%

(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione Structure

(S)-2-(1-Hydrox...

CAS#:70058-19-4

Literature: McArthur, Colin R.; Worster, Paul M.; Jiang, Ji-Long; Leznoff, Clifford Canadian Journal of Chemistry, 1982 , vol. 60, p. 1836 - 1841

~%

(S)-2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione Structure

(S)-2-(1-Hydrox...

CAS#:70058-19-4

Literature: Edman, Karl; Ahlgren, Ragnhild; Bengtsson, Malena; Bladh, Hakan; Baeckstroem, Stefan; Dahmen, Jan; Henriksson, Krister; Hillertz, Per; Hulikal, Vijakumar; Jerre, Anders; Kinchin, Liz; Kase, Charlotte; Lepistoe, Matti; Mile, Irene; Nilsson, Stinabritt; Smailagic, Amir; Taylor, John; Tjoernebo, Ann; Wissler, Lisa; Hansson, Thomas Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 11 p. 2571 - 2577

 Synonyms

(S)-N-carboxylic acid ethyl ester-1-phenyl-1,2,3,4-tetrahydroisoquinoline
(S)-ethyl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
1(S)-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester
(S)-1,2,3,4-tetrahydro-1-phenyl-isoquinoline-2-carboxylic acid ethyl ester
(S)-2-phtalimidopropanol
(S)-(+)-N-Phthalylalaninol
(1'S)-N-(1'-hydroxyethyl-2'-methyl)-1H-isoindole-1,3(2H)-dione
(+)-(S)-2-(2-hydroxy-1-methylethyl)-1H-isoindole-1,3(2H)-dione
(1S)-ethyl 1-phenyl-1,2,3,4-tetrahydro-2-isoquinoline carboxylate
(S)-2-phthalimido-1-propanol
(S)-2-phthalimidopropanol
(1S)-1-phenyl-1,2,3,4-tetrahydro-isoquinoline-2-carboxylic acid ethyl ester
ETHYL (S)-1-PHENYL-1,2,3,4-TETRAHYDRO-2-ISOQUINOLINECARBOXYLATE