Phenoxyacetyl chloride

Modify Date: 2024-01-12 11:38:55

Phenoxyacetyl chloride Structure
Phenoxyacetyl chloride structure
Common Name Phenoxyacetyl chloride
CAS Number 701-99-5 Molecular Weight 170.593
Density 1.2±0.1 g/cm3 Boiling Point 226.3±13.0 °C at 760 mmHg
Molecular Formula C8H7ClO2 Melting Point 28 - 30ºC
MSDS Chinese USA Flash Point 108.3±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name Phenoxyacetyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 226.3±13.0 °C at 760 mmHg
Melting Point 28 - 30ºC
Molecular Formula C8H7ClO2
Molecular Weight 170.593
Flash Point 108.3±0.0 °C
Exact Mass 170.013458
PSA 26.30000
LogP 2.07
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.525
Storage condition Store at RT.

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H314-H335
Supplemental HS Reacts violently with water.
Precautionary Statements P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R14;R34;R36/37
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3265 8/PG 2
WGK Germany 3
Packaging Group II
Hazard Class 8
HS Code 29189090

 Synthetic Route

~37%

Phenoxyacetyl chloride Structure

Phenoxyacetyl c...

CAS#:701-99-5

Literature: Wharton, Clifford J.; Wrigglesworth, Roger; Rowe, Michael Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 1 p. 29 - 39

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Phenoxyacetyl chloride Structure

Phenoxyacetyl c...

CAS#:701-99-5

Literature: Journal of the Indian Chemical Society, , vol. 68, # 6 p. 358 - 359

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Phenoxyacetyl chloride Structure

Phenoxyacetyl c...

CAS#:701-99-5

Literature: Journal of the Indian Chemical Society, , vol. 69, # 1 p. 45 - 46

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Phenoxyacetyl chloride Structure

Phenoxyacetyl c...

CAS#:701-99-5

Literature: Chem. Zentralbl., , vol. 69, # I p. 988

 Customs

HS Code 29189090

 Articles6

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Penicillin V acylases (PVAs, E.C.3.5.11) belong to the Ntn hydrolase super family of enzymes that catalyze the deacylation of the side chain from phenoxymethyl penicillin (penicillin V). Penicillin ac...

Preparation and properties of 5-phenylphenoxymethylpenicillin.

J. Med. Chem. 18(5) , 486-90, (1975)

Cycloaddition of azidoacetyl chloride to benzyl D-5,5-dimethyl-5-phenyl-2-thiazoline-4-carboxylate (1a) gave 5-phenyl-6alpha-azidopenicillanate (2a). By catalytic reduction of 2a and reaction with phe...

Transient silylation of the guanosine O6 and amino groups facilitates N-acylation.

Org. Lett. 6(15) , 2555-7, (2004)

[reaction: see text] The formation of a guanosine derivative silylated at both the O6 and amino groups was identified by (15)N NMR. This intermediate allows facile reaction with acetyl chloride or phe...

 Synonyms

MFCD00000726
EINECS 211-862-4
Acetyl chloride, 2-phenoxy-
Phenoxyacetyl chloride
2-phenoxyacetyl chloride
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