8-Dehydrocholesterol

Modify Date: 2024-01-09 21:18:24

8-Dehydrocholesterol Structure
8-Dehydrocholesterol structure
Common Name 8-Dehydrocholesterol
CAS Number 70741-38-7 Molecular Weight 384.63800
Density N/A Boiling Point N/A
Molecular Formula C27H44O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 8-Dehydrocholesterol


8-Dehydrocholesterol elevated concentration is one of the diagnostic biochemical hallmarks of classical Smith-Lemli-Opitz syndrome (SLOS).

 Names

Name (3S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
Synonym More Synonyms

 8-Dehydrocholesterol Biological Activity

Description 8-Dehydrocholesterol elevated concentration is one of the diagnostic biochemical hallmarks of classical Smith-Lemli-Opitz syndrome (SLOS).
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Batta AK, et al. Identification of 8-dehydrocholesterol (cholesta-5,8-dien-3 beta-ol) in patients with Smith-Lemli-Opitz syndrome. J Lipid Res. 1995 Apr;36(4):705-13.

 Chemical & Physical Properties

Molecular Formula C27H44O
Molecular Weight 384.63800
Exact Mass 384.33900
PSA 20.23000
LogP 7.45290

 Synonyms

8-Dehydrocholesterol
8-DHC
3b-Cholesta-5,8-dien-3-ol
Cholesta-5,8-dien-3beta-ol