(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol

Modify Date: 2024-01-02 15:23:13

(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol structure	Common Name	(1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol
	CAS Number	716-61-0	Molecular Weight	212.203
	Density	1.4±0.1 g/cm3	Boiling Point	451.9±45.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₂N₂O₄	Melting Point	163-165ºC
	MSDS	Chinese USA	Flash Point	227.1±28.7 °C
	Symbol	GHS07	Signal Word	Warning

Use of (1R,2R)-2-Amino-1-(4-nitrophenyl)propane-1,3-diol

Chloramphenicol base is a bioactive chemical.

Name	(R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	451.9±45.0 °C at 760 mmHg
Melting Point	163-165ºC
Molecular Formula	C₉H₁₂N₂O₄
Molecular Weight	212.203
Flash Point	227.1±28.7 °C
Exact Mass	212.079712
PSA	112.30000
LogP	0.13
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.630
Storage condition	−20°C

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY3100000

CHEMICAL NAME :: 1,3-Propanediol, 2-amino-1-(p-nitrophenyl)-, D-threo-(-)-

CAS REGISTRY NUMBER :: 716-61-0

LAST UPDATED :: 199406

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H12-N2-O4

MOLECULAR WEIGHT :: 212.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 2 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,207,1994

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26
RIDADR	UN 3259
WGK Germany	3
RTECS	TY3100000

[Studies on the resolution of racemic gossypol. IV. Use of threo (-) or (+)-1-(p-nitrophenyl)-1,3-dihydroxypropylamine-2 as the resolving agent].

Yao Xue Xue Bao 25(6) , 430-4, (1990)

Threo (-) or (+)-1-(p-nitrophenyl)-1,3-dihydroxypropylamine-2 was found to be a useful resolving agent for racemic gossypol. The optical and chemical stability of the condensate of enantiomeric gossyp...

Investigation of Batten disease with the yeast Saccharomyces cerevisiae.

Mol. Genet. Metab. 66(4) , 314-9, (1999)

The CLN3 gene, which encodes the protein whose absence is responsible for Batten disease, the most common inherited neurovisceral storage disease of childhood, was identified in 1995. The function of ...

High-performance liquid chromatographic determination of chloramphenicol and 2-amino-1-(p-nitrophenyl)-1,3-propanediol in pharmaceutical formulations.

J. Chromatogr. A. 170(1) , 282-7, (1979)