2-(Difluoromethoxy)benzaldehyde

Modify Date: 2024-01-02 17:49:12

2-(Difluoromethoxy)benzaldehyde Structure
2-(Difluoromethoxy)benzaldehyde structure
Common Name 2-(Difluoromethoxy)benzaldehyde
CAS Number 71653-64-0 Molecular Weight 172.129
Density 1.3±0.1 g/cm3 Boiling Point 226.6±30.0 °C at 760 mmHg
Molecular Formula C8H6F2O2 Melting Point N/A
MSDS Chinese USA Flash Point 88.4±19.4 °C

 Names

Name 2-(Difluoromethoxy)benzaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 226.6±30.0 °C at 760 mmHg
Molecular Formula C8H6F2O2
Molecular Weight 172.129
Flash Point 88.4±19.4 °C
Exact Mass 172.033585
PSA 26.30000
LogP 1.89
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.498

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2913000090

 Synthetic Route

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2-(Difluoromethoxy)benzaldehyde Structure

2-(Difluorometh...

CAS#:71653-64-0

Literature: US2002/35147 A1, ; US 20020035147 A1

~92%

2-(Difluoromethoxy)benzaldehyde Structure

2-(Difluorometh...

CAS#:71653-64-0

Literature: Shelyazhenko, S. V.; Fialkov, Yu. A.; Yagupol'skii, L. M. Journal of Organic Chemistry USSR (English Translation), 1992 , vol. 28, # 8.1 p. 1317 - 1324 Zhurnal Organicheskoi Khimii, 1992 , vol. 28, # 8 p. 1652 - 1660

~74%

2-(Difluoromethoxy)benzaldehyde Structure

2-(Difluorometh...

CAS#:71653-64-0

Literature: Li, Lingchun; Wang, Fei; Ni, Chuanfa; Hu, Jinbo Angewandte Chemie - International Edition, 2013 , vol. 52, # 47 p. 12390 - 12394 Angew. Chem., 2013 , vol. 125, # 47 p. 12616 - 12620,5

 Customs

HS Code 2913000090
Summary HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

 Articles3

More Articles
Effect of acyl chain length and branching on the enantioselectivity of Candida rugosa lipase in the kinetic resolution of 4-(2-difluoromethoxyphenyl)-substituted 1,4-dihydropyridine 3,5-diesters.

J. Org. Chem. 67(2) , 401-10, (2002)

Since 2,6-dimethyl-4-aryl-1,4-dihydropyridine 3,5-diesters themselves are not hydrolyzed by commercially available hydrolases, derivatives with spacers containing a hydrolyzable group were prepared. S...

Synthesis of 3-alkoxycarbonyl-6-alkylsulfanyl-4-[2-(difluoromethoxy) phenyl]-1, 4-dihydropyridines and related derivatives as analogs of cognition enhancer cerebrocrast. Krauze A, et al.

Chem. Heterocycl. Comp. 49(4) , 566-73, (2013)

Synthesis and enantioselective lipase-catalyzed kinetic resolution of methyl 6-(methoxycarbonyl-methyl) sulfanyl-1, 4-dihydropyridine-3-carboxylates. Andzans Z, et al.

Chem. Heterocycl. Comp. 49(13) , 421-27, (2013)

 Synonyms

Benzaldehyde, 2-(difluoromethoxy)-
MFCD00042251
2-(Difluoromethoxy)benzaldehyde
α,α-Difluoro-o-anisaldehyde
VHR BOYFF
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