1-Triazene,1-(4-methoxyphenyl)-3,3-dimethyl-

DATA ITEMS CITED :

8

MOLECULAR FORMULA :

C9-H13-N3-O

MOLECULAR WEIGHT :

179.25

WISWESSER LINE NOTATION :

1N1&NUNR DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

347 mg/kg

TOXIC EFFECTS :

Behavioral - irritability Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Liver - other changes

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

450 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1700 mg/kg/45W-I

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Tumorigenic - tumors at site of application

TYPE OF TEST :

Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :

Host-mediated assay

TEST SYSTEM :

Rodent - mouse Yeast - Saccharomyces cerevisiae

DOSE/DURATION :

71700 mg/kg

REFERENCE :

CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 9,365,1974